893407-18-6

• 常用中文名：2,2,2-三氟-1-(4'-(甲基磺酰基)-[1,1'-联苯]-4-基)乙酮
• 常用英文名：2,2,2-trifluoro-1-(4'-(Methylsulfonyl)biphenyl-4-yl)ethanone
• CAS号：893407-18-6
• 分子式：C₁₅H₁₁F₃O₃S
• 分子量：328.30600
• 发布时间：2016-03-04 05:56:07
• 更新时间：2025-08-21 18:05:12

名称

• 中文名: 2,2,2-三氟-1-(4'-(甲基磺酰基)-[1,1'-联苯]-4-基)乙酮
• 英文名: 2,2,2-Trifluoro-1-[4'-(methylsulfonyl)-4-biphenylyl]ethanone
• 中文别名: 奥当卡替中间体2; 奥当卡替(MK-0822)中间体; 奥当卡替(MK-0822)中间体 G; ODANACATIB中间体; 2,2,2-三氟-1-[4'-(甲基磺酰基)[1,1'-联苯]-4-基]乙酮/893-6; 2,2,2-三氟-1-[4'-(甲基磺酰基)[1,1'-联苯]-4-基]乙酮
• 英文别名: 1)2,2,2-trifluoro-1-(4'-(Methylsulfonyl)biphenyl-4-yl)ethanone; 2,2,2-Trifluoro-1-[4'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]ethanone; 4-(4-Methanesulfonyl-phenoxy)nitrobenzene; 2,2,2-trifluoro-1-[4-(4-methylsulfonylphenyl)phenyl]ethanone; Odanacatib intermediate; 4'-(4-methylsulfonylphenyl)-2,2,2-trifluoroacetophenone; 2,2,2-trifluoro-1-(4'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl)ethan-1-one; 1-(methylsulfonyl)-4-(4-nitrophenoxy)benzene; 4-(4-methylsulfonylphenoxy)-1-nitrobenzene; 2,2,2-Trifluoro-1-(4'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl)ethanone; Ethanone, 2,2,2-trifluoro-1-[4'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]; 2,2,2-trifluoro-1-(4'-methylsulfonyl-biphenyl-4-yl)-ethanone

物化性质

• 分子式: C₁₅H₁₁F₃O₃S
• 分子量: 328.30600
• 精确质量: 328.03800
• PSA: 59.59000
• LogP: 4.58290
• 储存条件: 室温

合成路线

16184-89-7 149104-88-1 ~93% 893407-18-6

文献：De Oliveira Lopes, Raquel; De Miranda, Amanda S.; Reichart, Benedikt; Glasnov, Toma; Kappe, C. Oliver; Simon, Robert C.; Kroutil, Wolfgang; Miranda, Leandro S.M.; Leal, Ivana C.R.; De Souza, Rodrigo O.M.A. Journal of Molecular Catalysis B: Enzymatic, 2014 , vol. 104, p. 101 - 107

893407-15-3 ~0% 893407-18-6 875272-88-1

文献：Dolman, Sarah J.; Gosselin, Francis; O'Shea, Paul D.; Davies, Ian W. Tetrahedron, 2006 , vol. 62, # 21 p. 5092 - 5098

875272-88-1 ~% 893407-18-6

文献：Dolman, Sarah J.; Gosselin, Francis; O'Shea, Paul D.; Davies, Ian W. Tetrahedron, 2006 , vol. 62, # 21 p. 5092 - 5098

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