942145-27-9

• 常用中文名：((S)-1-氨基-3-((R)-四氢-2H-吡喃-3-基)丙-2-基)(甲基)氨基甲酸叔丁酯
• 常用英文名：TERT-BUTYL ((S)-1-AMINO-3-((R)-TETRAHYDRO-2H-PYRAN-3-YL)PROPAN-2-YL)(METHYL)CARBAMATE
• CAS号：942145-27-9
• 分子式：C₁₄H₂₈N₂O₃
• 分子量：272.38400
• 发布时间：2019-01-14 08:32:14
• 更新时间：2024-01-23 02:04:21

名称

• 中文名: ((s)-1-氨基-3-((r)-四氢-2H-吡喃-3-基)丙烷-2-基)(甲基)氨基甲酸叔丁酯
• 英文名: tert-butyl N-[(2S)-1-amino-3-[(3R)-oxan-3-yl]propan-2-yl]-N-methylcarbamate
• 英文别名: CarbaMic acid,N-[(1S)-1-(aMinoMethyl)-2-[(3R)-tetrahydro-2H-pyran-3-yl]ethyl]-N-Methyl-,1,1-diMethylethyl ester; QC-4591; tert-butyl ((S)-1-aminomethyl-2-(R)-tetrahydro-pyran-3-yl-ethyl)-methyl-carbamate; 1,1-dimethylethyl {(1S)-2-amino-1-[(3R)-tetrahydro-2H-pyran-3-ylmethyl]ethyl}methylcarbamate; tert-Butyl ((S)-1-amino-3-((R)-tetrahydro-2H-pyran-3-yl)propan-2-yl)(methyl)carbamate

物化性质

• 密度: 1.026g/cm3
• 沸点: 370.2ºC at 760 mmHg
• 分子式: C₁₄H₂₈N₂O₃
• 分子量: 272.38400
• 闪点: 177.7ºC
• 精确质量: 272.21000
• PSA: 64.79000
• LogP: 2.69760
• 折射率: 1.479
• 储存条件: 2-8°C

安全

• 海关编码: 2932999099

合成路线

1013937-85-3 ~92% 942145-27-9

文献：VITAE PHARMACEUTICALS, INC. Patent: WO2008/156817 A2, 2008 ; Location in patent: Page/Page column 94; 99 ; WO 2008/156817 A2

942145-26-8 ~93% 942145-27-9

文献：Jia, Lanqi; Simpson, Robert D.; Yuan, Jing; Xu, Zhenrong; Zhao, Wei; Cacatian, Salvacion; Tice, Colin M.; Guo, Joan; Ishchenko, Alexey; Singh, Suresh B.; Wu, Zhongren; McKeever, Brian M.; Bukhtiyarov, Yuri; Johnson, Judith A.; Doe, Christopher P.; Harrison, Richard K.; McGeehan, Gerard M.; Dillard, Lawrence W.; Baldwin, John J.; Claremon, David A. ACS Medicinal Chemistry Letters, 2011 , vol. 2, # 10 p. 747 - 751

1093865-03-2 ~98% 942145-27-9

文献：VITAE PHARMACEUTICALS, INC. Patent: WO2009/154766 A1, 2009 ; Location in patent: Page/Page column 47 ; WO 2009/154766 A1

942145-24-6 ~% 942145-27-9

文献：Jia, Lanqi; Simpson, Robert D.; Yuan, Jing; Xu, Zhenrong; Zhao, Wei; Cacatian, Salvacion; Tice, Colin M.; Guo, Joan; Ishchenko, Alexey; Singh, Suresh B.; Wu, Zhongren; McKeever, Brian M.; Bukhtiyarov, Yuri; Johnson, Judith A.; Doe, Christopher P.; Harrison, Richard K.; McGeehan, Gerard M.; Dillard, Lawrence W.; Baldwin, John J.; Claremon, David A. ACS Medicinal Chemistry Letters, 2011 , vol. 2, # 10 p. 747 - 751

144978-35-8 ~% 942145-27-9

文献：Jia, Lanqi; Simpson, Robert D.; Yuan, Jing; Xu, Zhenrong; Zhao, Wei; Cacatian, Salvacion; Tice, Colin M.; Guo, Joan; Ishchenko, Alexey; Singh, Suresh B.; Wu, Zhongren; McKeever, Brian M.; Bukhtiyarov, Yuri; Johnson, Judith A.; Doe, Christopher P.; Harrison, Richard K.; McGeehan, Gerard M.; Dillard, Lawrence W.; Baldwin, John J.; Claremon, David A. ACS Medicinal Chemistry Letters, 2011 , vol. 2, # 10 p. 747 - 751

153080-81-0 ~% 942145-27-9

文献：Jia, Lanqi; Simpson, Robert D.; Yuan, Jing; Xu, Zhenrong; Zhao, Wei; Cacatian, Salvacion; Tice, Colin M.; Guo, Joan; Ishchenko, Alexey; Singh, Suresh B.; Wu, Zhongren; McKeever, Brian M.; Bukhtiyarov, Yuri; Johnson, Judith A.; Doe, Christopher P.; Harrison, Richard K.; McGeehan, Gerard M.; Dillard, Lawrence W.; Baldwin, John J.; Claremon, David A. ACS Medicinal Chemistry Letters, 2011 , vol. 2, # 10 p. 747 - 751

上下游产品

上游产品  5
942145-26-8 1093865-03-2 942145-24-6 144978-35-8
153080-81-0
下游产品  1
1013937-63-7

海关

海关编码	2932999099
中文概述	2932999099. 其他仅含氧杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%