22912-25-0

• 常用中文名：Cyclohexanecarbonitrile,1-(1-pyrrolidinyl)-
• 常用英文名：Cyclohexanecarbonitrile,1-(1-pyrrolidinyl)-
• CAS号：22912-25-0
• 分子式：C₁₁H₁₈N₂
• 分子量：178.27400
• 发布时间：2018-06-22 06:56:36
• 更新时间：2024-01-23 00:10:16

名称

• 英文名: 1-pyrrolidin-1-ylcyclohexane-1-carbonitrile
• 英文别名: 1-pyrrolidinocyclohexanecarbonitrile; Cyclohexanecarbonitrile,1-pyrrolidino; Cyclohexanecarbonitrile,1-(1-pyrrolidinyl); 2-pyrrolidin-1-ylcyclohexanecarbonitrile; 1-(1-Cyanocyclohexyl)-pyrrolidine; 1-pyrrolidin-1-yl-cyclohexanecarbonitrile

物化性质

• 密度: 1.02g/cm3
• 沸点: 291.3ºC at 760mmHg
• 分子式: C₁₁H₁₈N₂
• 分子量: 178.27400
• 闪点: 119.2ºC
• 精确质量: 178.14700
• PSA: 27.03000
• LogP: 2.24658
• 蒸汽压: 0.00196mmHg at 25°C
• 折射率: 1.518

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : GU7740000 CHEMICAL NAME : Cyclohexanecarbonitrile, 1-(1-pyrrolidinyl)- CAS REGISTRY NUMBER : 22912-25-0 BEILSTEIN REFERENCE NO. : 1367051 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C11-H18-N2 MOLECULAR WEIGHT : 178.31 WISWESSER LINE NOTATION : T5NTJ A- AL6TJ ACN HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 39 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory stimulation REFERENCE : JJATDK JAT, Journal of Applied Toxicology. (John Wiley & Sons Ltd., Baffins Lane, Chichester, W. Sussex PO19 1UD, UK) V.1- 1981- Volume(issue)/page/year: 2,16,1982 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 10 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#03415

合成路线

123-75-1 7677-24-9 108-94-1 ~82% 22912-25-0

文献：Surya Prakash; Bychinskaya, Inessa; Marinez, Eric R.; Mathew, Thomas; Olah, George A. Catalysis Letters, 2013 , vol. 143, # 4 p. 303 - 312

123-75-1 143-33-9 108-94-1 ~88% 22912-25-0

文献：Ogunbadeniyi, Alaba M.; Adejare, Adeboye Journal of Fluorine Chemistry, 2002 , vol. 114, # 1 p. 39 - 42

123-75-1 151-50-8 108-94-1 ~79% 22912-25-0

文献：Trost, Barry M.; Spagnol, Michel D. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1995 , # 17 p. 2083 - 2096

上下游产品

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123-75-1 7677-24-9 108-94-1 143-33-9
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1125-99-1