119813-10-4

• 常用中文名：卡折来新
• 常用英文名：2-Benzofurancarboxamide,N-[2-[[(1S)-1-(chloromethyl)-1,6-dihydro-8-methyl-5-[[(phenylamino)carbonyl]oxy]benzo[1,2-b:4,3-b']dipyrrol-3(2H)-yl]carbonyl]-1H-indol-5-yl]-6-(diethylamino)-
• CAS号：119813-10-4
• 分子式：C₄₁H₃₇ClN₆O₅
• 分子量：729.22300
• 发布时间：2018-03-26 08:00:00
• 更新时间：2024-01-17 19:30:34

名称

• 中文名: 卡折来新
• 英文名: [(8S)-8-(chloromethyl)-6-[5-[[6-(diethylamino)-1-benzofuran-2-carbonyl]amino]-1H-indole-2-carbonyl]-1-methyl-7,8-dihydro-3H-pyrrolo[3,2-e]indol-4-yl] N-phenylcarbamate
• 英文别名: Carzelesin; Carzelesin (USAN/INN)

物化性质

• 密度: 1.426g/cm3
• 沸点: 938.9ºC at 760mmHg
• 分子式: C₄₁H₃₇ClN₆O₅
• 分子量: 729.22300
• 闪点: 521.6ºC
• 精确质量: 728.25100
• PSA: 135.70000
• LogP: 9.60700
• 折射率: 1.762

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : DF6473200 CAS REGISTRY NUMBER : 119813-10-4 LAST UPDATED : 199712 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C41-H37-Cl-N6-O5 MOLECULAR WEIGHT : 729.29 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD10 - Lethal Dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 40 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 21,245,1996 TYPE OF TEST : LD10 - Lethal Dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 280 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 21,245,1996

合成路线

112836-67-6 ~% 119813-10-4

文献：Fukuda, Yasumichi; Furuta, Hirosuke; Shiga, Futoshi; Asahina, Yoshikazu; Terashima, Shiro Heterocycles, 1997 , vol. 45, # 12 p. 2303 - 2308

110314-50-6 ~% 119813-10-4

文献：Fukuda, Yasumichi; Furuta, Hirosuke; Shiga, Futoshi; Asahina, Yoshikazu; Terashima, Shiro Heterocycles, 1997 , vol. 45, # 12 p. 2303 - 2308

176685-39-5 ~% 119813-10-4

文献：Fukuda, Yasumichi; Furuta, Hirosuke; Shiga, Futoshi; Asahina, Yoshikazu; Terashima, Shiro Heterocycles, 1997 , vol. 45, # 12 p. 2303 - 2308

176685-38-4 ~% 119813-10-4

文献：Fukuda, Yasumichi; Furuta, Hirosuke; Shiga, Futoshi; Asahina, Yoshikazu; Terashima, Shiro Heterocycles, 1997 , vol. 45, # 12 p. 2303 - 2308

110314-51-7 ~% 119813-10-4

文献：Fukuda, Yasumichi; Furuta, Hirosuke; Shiga, Futoshi; Asahina, Yoshikazu; Terashima, Shiro Heterocycles, 1997 , vol. 45, # 12 p. 2303 - 2308

110314-54-0 ~% 119813-10-4

文献：Fukuda, Yasumichi; Furuta, Hirosuke; Shiga, Futoshi; Asahina, Yoshikazu; Terashima, Shiro Heterocycles, 1997 , vol. 45, # 12 p. 2303 - 2308

103-71-9 119813-16-0 ~87% 119813-10-4

文献：Fukuda, Yasumichi; Furuta, Hirosuke; Shiga, Futoshi; Asahina, Yoshikazu; Terashima, Shiro Heterocycles, 1997 , vol. 45, # 12 p. 2303 - 2308

上下游产品

上游产品  6
103-71-9 112836-67-6 110314-50-6 176685-39-5
110314-51-7 110314-54-0
下游产品  0