2933-94-0

• 常用中文名：托利洛尔
• 常用英文名：toliprolol
• CAS号：2933-94-0
• 分子式：C₁₃H₂₁NO₂
• 分子量：223.31100
• 发布时间：2018-09-25 20:28:14
• 更新时间：2024-01-11 14:58:23

名称

• 中文名: 托利洛尔
• 英文名: 1-(3-methylphenoxy)-3-(propan-2-ylamino)propan-2-ol
• 英文别名: 3-isopropylamino-1-(3-methyl-phenoxy)-2-propanol; 1-(3-Methyl-phenoxy)-3-isopropylamino-propanol-(2); MHIP; 1-(Isopropylamino)-3-(m-tolyloxy)-2-propanol; Toliprololum [INN-Latin]; Isopropylamino-1-m-tolyloxy-3-propan-2-ol [German]; Toliprolol; 2-Propanol,1-(isopropylamino)-3-(m-tolyloxy)

物化性质

• 密度: 1.018g/cm3
• 沸点: 359.4ºC at 760mmHg
• 分子式: C₁₃H₂₁NO₂
• 分子量: 223.31100
• 闪点: 171.2ºC
• 精确质量: 223.15700
• PSA: 41.49000
• LogP: 2.12360
• 蒸汽压: 8.6E-06mmHg at 25°C
• 折射率: 1.513

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : UB7578500 CHEMICAL NAME : 2-Propanol, 1-(isopropylamino)-3-(m-tolyloxy)- CAS REGISTRY NUMBER : 2933-94-0 LAST UPDATED : 199706 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C13-H21-N-O2 MOLECULAR WEIGHT : 223.35 WISWESSER LINE NOTATION : 1Y1M1YQ1OR C1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 28200 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 22,869,1972

安全

• 海关编码: 2922299090

合成路线

2186-25-6 75-31-0 ~95% 2933-94-0

文献：Stephenson, Karin A.; Wilson, Alan A.; Meyer, Jeffrey H.; Houle, Sylvain; Vasdev, Neil Journal of Medicinal Chemistry, 2008 , vol. 51, # 16 p. 5093 - 5100

42865-04-3 75-31-0 ~% 2933-94-0

文献：Zaagsma Journal of Medicinal Chemistry, 1979 , vol. 22, # 4 p. 441 - 449

108-39-4 ~% 2933-94-0

文献：Pchelka, Beata; Plenkiewicz, Jan Organic Preparations and Procedures International, 1998 , vol. 30, # 1 p. 87 - 90

上下游产品

上游产品  4
2186-25-6 75-31-0 42865-04-3 108-39-4
下游产品  0

海关

海关编码	2922299090
中文概述	2922299090. 其他氨基(萘酚、酚)及醚、酯〔包括它们的盐, 但含有一种以上含氧基的除外〕. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装
Summary	2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%