136949-58-1

• 常用中文名：碘比醇
• 常用英文名：Iobitridol
• CAS号：136949-58-1
• 分子式：C₂₀H₂₈I₃N₃O₉
• 分子量：835.164
• 相关类别： 原料药 诊断用药 器官功能检查剂
• 发布时间：2018-07-07 20:42:32
• 更新时间：2026-07-07 13:34:41

名称

• 中文名: 碘比醇
• 英文名: iobitridol
• 中文别名: Iobitridol试剂; 碘克沙醇杂质20; 碘比醇对照杂质; N1,N3-双(2,3-二羟基丙基)-5-[[3-羟基-2-(羟甲基)-1-氧代丙基]氨基]-2,4,6-三碘-N1,N3-二甲基-1,3-苯二甲酰胺; 碘比醇Iobitridol; 碘比醇杂质N1
• 英文别名: Iodinated alcohol; Optiject; N,N'-bis(2,3-dihydroxypropyl)-5-{[3-hydroxy-2-(hydroxymethyl)propanoyl]amino}-2,4,6-triiodo-N,N'-dimethylbenzene-1,3-dicarboxamide; IOBITRIDOL; 1,3-Benzenedicboxamide, N1,N3-bis(2,3-dihydroxypropyl)-5-[[3-hydroxy-2-(hydroxymethyl)-1-oxopropyl]amino]-2,4,6-triiodo-N1,N3-dimethyl; Iobitrido; Xenetix; N1,N3-Bis(2,3-dihydroxypropyl)-5-[[3-hydroxy-2-(hydroxyMethyl)-1-oxopropyl]amino]-2,4,6-triiodo-N1,N3-diMethyl-1,3-benzenedicboxaMide; Iobitridol [INN]; 1,3-Benzenedicarboxamide,N,N'-bis(2,3-dihydroxypropyl)-5-((5-hydroxy-2-(hydroxymethyl)-1-oxopropyl)amino)-2,4,6-triiodo-N,N'-dimethyl; N,N'-Bis(2,3-dihydroxypropyl)-5-((5-hydroxy-2-(hydroxymethyl)-1-oxopropyl)amino)-2,4,6-triiodo-N,N'-dimethyl-1,3-benzenedicarboxamide; Xenetix 300; N,N'-Bis(2,3-dihydroxypropyl)-5-((5-hydroxy-2-(hydroxymethyl)-1-oxopropyl)amino)-2,4,6-triiodo-N,N'-dimethyl-1,3-benzenedicboxamide; 1-N,3-N-bis(2,3-dihydroxypropyl)-5-[[3-hydroxy-2-(hydroxymethyl)propanoyl]amino]-2,4,6-triiodo-1-N,3-N-dimethylbenzene-1,3-dicarboxamide; Iodixanol Impurity 20; N,N'-Bis(2,3-dihydroxypropyl)-5-{[3-hydroxy-2-(hydroxymethyl)propanoyl]amino}-2,4,6-triiodo-N,N'-dimethylisophthalamide; N,N'-Bis(2,3-dihydroxypropyl)-5-(2-(hydroxymethyl)hydracrylamido)-2,4,6-triiodo-N,N'-dimethylisophthalamide; Iobitridol Impurity; Iobitridol Impurity N1; Iobitridol (JAN/INN); Iobitridol //BP

物化性质

• 密度: 2.2±0.1 g/cm3
• 沸点: 1010.9±65.0 °C at 760 mmHg
• 熔点: 196-199°C
• 分子式: C₂₀H₂₈I₃N₃O₉
• 分子量: 835.164
• 闪点: 565.2±34.3 °C
• 精确质量: 834.895935
• PSA: 191.10000
• LogP: -3.23
• 蒸汽压: 0.0±0.3 mmHg at 25°C
• 折射率: 1.726
• 储存条件: Refrigerator

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : CZ2229500 CHEMICAL NAME : 1,3-Benzenedicarboxamide, N,N'-bis(2,3-dihydroxypropyl)-5-((5-hydroxy-2-(hydrox ymethyl)- 1-oxopropyl)amino)-2,4,6-triiodo-N,N'-dimethyl- CAS REGISTRY NUMBER : 136949-58-1 LAST UPDATED : 199703 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C20-H28-I3-N3-O9 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 33785 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARASA5 Acta Radiologica, Supplementum. (Acta Radiologica, POB 7449, S-10391 Stockholm, Sweden) No.1- 1921- Volume(issue)/page/year: 400,17,1996 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 36418 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes REFERENCE : ARASA5 Acta Radiologica, Supplementum. (Acta Radiologica, POB 7449, S-10391 Stockholm, Sweden) No.1- 1921- Volume(issue)/page/year: 400,17,1996