18588-57-3

• 常用中文名：2,4-Pyrimidinediamine,5-(3,4-dichlorophenyl)-6-ethyl-
• 常用英文名：2,4-Pyrimidinediamine,5-(3,4-dichlorophenyl)-6-ethyl-
• CAS号：18588-57-3
• 分子式：C₁₂H₁₂Cl₂N₄
• 分子量：283.15600
• 发布时间：2016-12-10 04:41:53
• 更新时间：2024-01-23 17:59:18

名称

• 英文名: 5-(3,4-dichlorophenyl)-6-ethylpyrimidine-2,4-diamine
• 英文别名: Etoprine (USAN); ETOPRINE; 5-(3,4-dichloro-phenyl)-6-ethyl-pyrimidine-2,4-diamine; 6-ethyl-5-(3,4-dichloro-phenyl)-pyrimidine-2,4-diyldiamine; Ethodichlorophen; 6-Aethyl-5-(3,4-dichlor-phenyl)-pyrimidin-2,4-diyldiamin; 2,4-Diamino-5-(3,4-dichlor-phenyl)-6-ethyl-pyrimidin; DDEP; 2,4-diamino-5-(3',4'-dichlorophenyl)-6-ethylpyrimidine

物化性质

• 密度: 1.398g/cm3
• 沸点: 518.3ºC at 760 mmHg
• 分子式: C₁₂H₁₂Cl₂N₄
• 分子量: 283.15600
• 闪点: 267.3ºC
• 精确质量: 282.04400
• PSA: 77.82000
• LogP: 4.33960
• 蒸汽压: 7.59E-11mmHg at 25°C
• 折射率: 1.661

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : UV8150000 CHEMICAL NAME : Pyrimidine, 2,4-diamino-5-(3,4-dichlorophenyl)-6-ethyl- CAS REGISTRY NUMBER : 18588-57-3 BEILSTEIN REFERENCE NO. : 0244129 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C12-H12-Cl2-N4 MOLECULAR WEIGHT : 283.18 WISWESSER LINE NOTATION : T6N CNJ BZ DZ ER CG DG F2 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 66 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value MUTATION DATA TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Escherichia coli DOSE/DURATION : 1 mg/disc REFERENCE : APMBAY Applied Microbiology. (Washington, DC) V.1-30, 1953-75. For publisher information, see AEMIDF. Volume(issue)/page/year: 6,23,1958

安全

• 海关编码: 2933599090

合成路线

186581-53-3 77186-55-1 ~% 18588-57-3

文献：Russell; Hitchings Journal of the American Chemical Society, 1951 , vol. 73, p. 3763,3766

77186-55-1 ~% 18588-57-3

文献：Tarnchompoo, Bongkoch; Sirichaiwat, Chawanee; Phupong, Worrapong; Intaraudom, Chakapong; Sirawaraporn, Worachart; Kamchonwongpaisan, Sumalee; Vanichtanankul, Jarunee; Thebtaranonth, Yodhathai; Yuthavong, Yongyuth Journal of Medicinal Chemistry, 2002 , vol. 45, # 6 p. 1244 - 1252

1445-45-0 77186-55-1 ~% 18588-57-3

文献：Burroughs Wellcome and Co. Patent: US2594309 , 1950 ;

3218-49-3 ~% 18588-57-3

文献：Russell; Hitchings Journal of the American Chemical Society, 1951 , vol. 73, p. 3763,3766

上下游产品

上游产品  4
3218-49-3 186581-53-3 77186-55-1 1445-45-0
下游产品  0

海关

海关编码	2933599090
中文概述	2933599090. 其他结构上有嘧啶环的化合物(包括其他结构上有哌嗪环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%