7376-66-1

• 常用中文名：地特诺
• 常用英文名：4-[1-Hydroxy-2-(isopropylamino)ethyl]phenol
• CAS号：7376-66-1
• 分子式：C₁₁H₁₇NO₂
• 分子量：195.25800
• 发布时间：2018-10-02 12:07:45
• 更新时间：2025-08-25 12:13:12

名称

• 中文名: 地特诺
• 英文名: 4-[1-Hydroxy-2-(isopropylamino)ethyl]phenol
• 英文别名: para-phenylethynylphenyl isocyanate; Paraproterenol

物化性质

• 密度: 1.099 g/cm3
• 沸点: 355.9ºC at 760mmHg
• 分子式: C₁₁H₁₇NO₂
• 分子量: 195.25800
• 闪点: 143ºC
• 精确质量: 195.12600
• PSA: 52.49000
• LogP: 1.81450
• 折射率: 1.55

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : DO6530000 CHEMICAL NAME : Benzyl alcohol, p-hydroxy-alpha-isopropylaminomethyl- CAS REGISTRY NUMBER : 7376-66-1 BEILSTEIN REFERENCE NO. : 2098796 LAST UPDATED : 199612 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C11-H17-N-O2 MOLECULAR WEIGHT : 195.29 WISWESSER LINE NOTATION : QR DYQ1MY1&1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 370 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 106,341,1952 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 144 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 106,341,1952 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 1800 mg/kg/12W-I TOXIC EFFECTS : Cardiac - pulse rate increase, without fall in BP Vascular - BP lowering not characterized in autonomic section REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 89,297,1947

安全

• 海关编码: 2922509090

合成路线

4254-67-5 ~% 7376-66-1

文献：Barlow; Main; Snow Journal of Medicinal Chemistry, 1981 , vol. 24, # 3 p. 315 - 322

99985-57-6 ~% 7376-66-1

文献：Corrigan; Langerman; Moore Journal of the American Chemical Society, 1945 , vol. 67, p. 1894

5324-15-2 ~% 7376-66-1

文献：Corrigan; Langerman; Moore Journal of the American Chemical Society, 1945 , vol. 67, p. 1894

38737-90-5 ~% 7376-66-1

文献：Asscher Recueil des Travaux Chimiques des Pays-Bas, 1949 , vol. 68, p. 967

108-95-2 ~% 7376-66-1

文献：Asscher Recueil des Travaux Chimiques des Pays-Bas, 1949 , vol. 68, p. 967

上下游产品

上游产品  4
4254-67-5 5324-15-2 38737-90-5 108-95-2
下游产品  0

海关

海关编码	2922509090
中文概述	2922509090. 其他氨基醇酚、氨基酸酚及其他含氧基氨基化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件：AB. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装
监管条件	A.入境货物通关单 B.出境货物通关单
检验检疫	R.进口食品卫生监督检验 S.出口食品卫生监督检验
Summary	2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%