3109-12-4

• 常用中文名：1-(4-fluorophenyl)-4-(4-hydroxy-4-phenylpiperidin-1-yl)butan-1-one
• 常用英文名：1-(4-fluorophenyl)-4-(4-hydroxy-4-phenylpiperidin-1-yl)butan-1-one
• CAS号：3109-12-4
• 分子式：C₂₁H₂₄FNO₂
• 分子量：341.41900
• 发布时间：2016-12-17 02:45:59
• 更新时间：2024-01-02 18:17:30

名称

• 英文名: 1-(4-fluorophenyl)-4-(4-hydroxy-4-phenylpiperidin-1-yl)butan-1-one
• 英文别名: Dechloro Haloperidol; UNII-QKZ09O18R6; Haloperidol impurity B; Deschlorhaloperidol; Haloperidol Impurity 1

物化性质

• 密度: 1.171g/cm3
• 沸点: 504.4ºC at 760mmHg
• 分子式: C₂₁H₂₄FNO₂
• 分子量: 341.41900
• 闪点: 258.9ºC
• 精确质量: 341.17900
• PSA: 40.54000
• LogP: 3.71010
• 折射率: 1.573

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : EU2760000 CHEMICAL NAME : Butyrophenone, 4'-fluoro-4-(4-hydroxy-4-phenylpiperidino)- CAS REGISTRY NUMBER : 3109-12-4 BEILSTEIN REFERENCE NO. : 0316568 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C21-H24-F-N-O2 MOLECULAR WEIGHT : 341.46 WISWESSER LINE NOTATION : T6NTJ A3VR DF& DQ DR HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 25 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#12459

安全

• 海关编码: 2933399090

合成路线

462-06-6 ~% 3109-12-4

文献：Journal of Medicinal and Pharmaceutical Chemistry, , vol. 1, p. 281,284

220525-47-3 ~% 3109-12-4

文献：Journal of Medicinal and Pharmaceutical Chemistry, , vol. 1, p. 281,284

40807-61-2 3874-54-2 ~% 3109-12-4

文献：Journal of Medicinal and Pharmaceutical Chemistry, , vol. 1, p. 281,284

上下游产品

上游产品  3
462-06-6 40807-61-2 3874-54-2
下游产品  0

海关

海关编码	2933399090
中文概述	2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%