154093-72-8

• 常用中文名：8-羟基-6-氟加替沙星
• 常用英文名：1-CYCLOPROPYL-6,7-DIFLUORO-8-HYDROXY-4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID
• CAS号：154093-72-8
• 分子式：C₁₃H₉F₂NO₄
• 分子量：281.21200
• 发布时间：2018-12-25 17:37:26
• 更新时间：2026-08-06 16:57:31

名称

• 中文名: 1-环丙基-6, 7-二氟-8-羟基-4-氧代-1, 4-二氢喹啉-3-甲酸
• 英文名: 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-hydroxy-4-oxo-3-quinolinecarboxylic Acid
• 中文别名: 1-环丙基-6,7-二氟-8-羟基-4-氧代-1,4-二氢喹啉-3-羧酸; 1-环丙基-6,7-二氟-1,4-二氢-8-羟基-4-氧代-3-喹啉羧酸; 加替沙星RC B; 莫西沙星二氟羟基酸; 莫西沙星杂质Z; 莫西沙星杂质Z1; 莫西沙星杂质/1-环丙基-6, 7-二氟-8-羟基-4-氧代-1, 4-二氢喹啉-3-甲酸; 莫西沙星相关杂质(RC-3); 莫西沙星杂质E2; 8-羟基莫西沙星喹啉; 盐酸莫西沙星杂质11; 莫西沙星杂质23; 加替沙星美国药典杂质B; 加替沙星杂质B; 莫西沙星二氟羟基酸杂质; 1-Cyclopropyl-6,7-difluoro-8-hydroxy-4-oxo-1,4-dihydroquinoline-3-cboxylic acid|||1-环丙基-6, 7-二氟-8-羟基-4-氧代-1, 4-二氢喹啉-3-甲酸
• 英文别名: Moxifloxacin Difluoro Hydroxy Acid Impurity (Gatifloxacin Related Compound B); Moxifloxacin Difluoro Hydroxy Impurity; Difluorohydroxy gatifloxacin; Moxifloxacin impurity 18/Moxifloxacin Hydroxy Quinoline Impurity/1-Cyclopropyl-6,7-difluoro-8-hydroxy-4-oxo-1,4-dihydroquinoline-3-cboxylic acid; Moxifloxacin Difluoro Hydroxy Acid Impurity; Gatifloxacin IMpurity B; Gatifloxacin Impurity 2; 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-hydroxy-4-oxo-3-quinolinecboxylic Acid; 1-cyclopropyl-6,7-difluoro-8-hydroxy-4-oxoquinoline-3-cboxylic acid; Mosisasin Impurity E2; 1-cyclopropyl-6,7-difluoro-8-hydroxy-4-oxoquinoline-3-carboxylic acid; Gatifloxacin Related Compound B/Moxifloxacin Difluoro Hydroxy Acid Impurity; 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-hydroxy-4-oxo-quinolin-3-cboxylic acid; 1-cyclopropyl-6,7-difluoro; Moxifloxacin hydroxyquinoline impurities; 3-Quinolinecboxylic acid, 1-cyclopropyl-6,7-difluoro-1,4-dihydro-8-hydroxy-4-oxo; Moxifloxacin Impurity 23; Gatifloxacin Impurity: 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-hydroxy- 4-oxo-3-quinolinecboxylic acid; 1-cyclopropyl-6,7-difluoro-8-hydroxy-4-oxo-1,4-dihydroquinoline-3-cboxylic acid; Gatifloxacin hydroxy acid impurity; Gatifloxacin RC B

物化性质

• 分子式: C₁₃H₉F₂NO₄
• 分子量: 281.21200
• 精确质量: 281.05000
• PSA: 79.53000
• LogP: 2.01840
• 储存条件: 室温，干燥密封

安全

• 海关编码: 2933499090

合成路线

112811-72-0 ~87% 154093-72-8

文献：KRKA, TOVARNA ZDRAVIL, D.D., NOVO MESTO Patent: WO2006/4561 A1, 2006 ; Location in patent: Page/Page column title page; 4; 12-13 ;

112811-71-9 ~90% 154093-72-8

文献：Institute of Medicinal Biotechnology, Chinese Acadamy of Medical Sciences; Zhe Jiang Medecine Co., Ltd. Xinchang Pharmaceutical Factory Patent: EP1767536 A1, 2007 ; Location in patent: Page/Page column 8 ;

上下游产品

上游产品  2
112811-72-0 112811-71-9
下游产品  1
112811-72-0

海关

海关编码	2933499090
中文概述	2933499090. 其他含喹琳或异喹啉环系的化合物〔但未进一步稠合的〕. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%