86111-26-4

• 常用中文名：秦哚昔芬
• 常用英文名：D 16726
• CAS号：86111-26-4
• 分子式：C₂₁H₂₁NO₄
• 分子量：351.39600
• 发布时间：2018-04-15 08:00:00
• 更新时间：2024-01-05 05:37:57

名称

• 中文名: 秦哚昔芬
• 英文名: [4-(5-acetyloxy-1-ethyl-3-methylindol-2-yl)phenyl] acetate
• 英文别名: Zindoxifenum [Latin]; 1H-Indol-5-ol,2-(4-(acetyloxy)phenyl)-1-ethyl-3-methyl-,acetate (ester); Zindoxifeno [Spanish]; 5-Acetoxy-2-(4-acetoxyphenyl)-1-ethyl-3-methylindole; 2-(4-(Acetyloxy)phenyl)-1-ethyl-3-methyl-1H-indol-5-ol acetate (ester); Zindoxifene

物化性质

• 密度: 1.17g/cm3
• 沸点: 508.3ºC at 760 mmHg
• 分子式: C₂₁H₂₁NO₄
• 分子量: 351.39600
• 闪点: 261.2ºC
• 精确质量: 351.14700
• PSA: 57.53000
• LogP: 4.48720
• 折射率: 1.577

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : NM2445000 CHEMICAL NAME : 1H-Indol-5-ol, 2-(4-(acetyloxy)phenyl)-1-ethyl-3-methyl-, acetate (ester) CAS REGISTRY NUMBER : 86111-26-4 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C21-H21-N-O4 MOLECULAR WEIGHT : 351.43 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 5 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 10,281,1985 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 5 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 10,281,1985

安全

• 海关编码: 2933990090

合成路线

91444-18-7 ~% 86111-26-4

文献：Angerer, Erwin von; Prekajac, Jelica; Strohmeier, Josef Journal of Medicinal Chemistry, 1984 , vol. 27, # 11 p. 1439 - 1447

104-94-9 ~% 86111-26-4

文献：Angerer, Erwin von; Prekajac, Jelica; Strohmeier, Josef Journal of Medicinal Chemistry, 1984 , vol. 27, # 11 p. 1439 - 1447

91444-33-6 ~% 86111-26-4

文献：Angerer, Erwin von; Prekajac, Jelica; Strohmeier, Josef Journal of Medicinal Chemistry, 1984 , vol. 27, # 11 p. 1439 - 1447

108-24-7 86111-11-7 ~% 86111-26-4

文献：Angerer, Erwin von; Prekajac, Jelica; Strohmeier, Josef Journal of Medicinal Chemistry, 1984 , vol. 27, # 11 p. 1439 - 1447

21086-33-9 ~% 86111-26-4

文献：Angerer, Erwin von; Prekajac, Jelica; Strohmeier, Josef Journal of Medicinal Chemistry, 1984 , vol. 27, # 11 p. 1439 - 1447

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%