应用 高分子量聚-γ-谷氨酸(γPGA)被证明可以在C57BL/6小鼠中增加NK细胞介导的细胞毒性水平以及 INF-γ分泌。 已经评估了可生物降解的γ-PGA纳米颗粒作为抗原递送载体 以及递送流感病毒血凝素(HA)疫苗的应用。 γ-PGA的其他生命科学应用包括用于可生物降解的纤维和纳米纤维片、水凝胶和冷冻保护剂。 Description High molecular weight poly-γ-glutamic acid (γPGA) was found to increase levels of NK cell-mediated cytotoxicity and INF-γ secretion in C57BL/6 mice. Biodegradable γ-PGA nanoparticles have been evaluated for use as antigen delivery carriers and delivery of influenza virus hemagglutin (HA) vaccine. Additional life science applications for γ-PGA include uses in biodegradable fibers and nanofiber sheets, hydrogels, and cryoprotectants.