18588-50-6

• 常用中文名：2,4-DIAMINO-6-METHYL-5-PHENYLPYRIMIDINE
• 常用英文名：2,4-DIAMINO-6-METHYL-5-PHENYLPYRIMIDINE
• CAS号：18588-50-6
• 分子式：C₁₁H₁₂N₄
• 分子量：200.24000
• 发布时间：2016-02-03 15:54:42
• 更新时间：2025-09-10 10:08:35

名称

• 英文名: 6-methyl-5-phenylpyrimidine-2,4-diamine
• 英文别名: 2,4-Diamino-6-methyl-5-phenylpyrimidine; 2,4-Diamino-5-phenyl-6-methylpyrimidine; Pyrimidine,2,4-diamino-6-methyl-5-phenyl; 2,4-Diamino-5-phenyl-6-methylpyrimidin; 6-Methyl-5-phenyl-2,4-pyrimidinediamine; 6-methyl-5-phenyl-pyrimidine-2,4-diyldiamine; 6-methyl-5-phenyl-pyrimidine-2,4-diamine; IEM-687; 6-Methyl-5-phenyl-pyrimidin-2,4-diyldiamin

物化性质

• 密度: 1.236g/cm3
• 沸点: 431.9ºC at 760 mmHg
• 分子式: C₁₁H₁₂N₄
• 分子量: 200.24000
• 闪点: 244.9ºC
• 精确质量: 200.10600
• PSA: 77.82000
• LogP: 2.77880
• 蒸汽压: 1.16E-07mmHg at 25°C
• 折射率: 1.667

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : UV8198000 CHEMICAL NAME : Pyrimidine, 2,4-diamino-6-methyl-5-phenyl- CAS REGISTRY NUMBER : 18588-50-6 BEILSTEIN REFERENCE NO. : 0012007 LAST UPDATED : 199612 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C11-H12-N4 MOLECULAR WEIGHT : 200.27 WISWESSER LINE NOTATION : T6N CNJ BZ DZ ER& F1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 50 mg/kg SEX/DURATION : female 14 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Embryo or Fetus - cytological changes (including somatic cell genetic material) REFERENCE : SJDBA9 Soviet Journal Developmental Biology (English Translation). Translation of Ontogenez. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) V.1- 1970- Volume(issue)/page/year: 7,45,1976 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 25 mg/kg SEX/DURATION : female 9 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) REFERENCE : AAGEAA Arkhiv Anatomii, Gistologii i Embriologii. Archives of Anatomy, Histology and Embryology. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-101, 1916-91. Discontinued Volume(issue)/page/year: 71(7),29,1976 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 100 mg/kg SEX/DURATION : female 9 day(s) after conception TOXIC EFFECTS : Reproductive - Specific Developmental Abnormalities - other developmental abnormalities REFERENCE : AAGEAA Arkhiv Anatomii, Gistologii i Embriologii. Archives of Anatomy, Histology and Embryology. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-101, 1916-91. Discontinued Volume(issue)/page/year: 71(7),29,1976

安全

• 海关编码: 2933599090

合成路线

140-29-4 ~% 18588-50-6

文献：Tarnchompoo, Bongkoch; Sirichaiwat, Chawanee; Phupong, Worrapong; Intaraudom, Chakapong; Sirawaraporn, Worachart; Kamchonwongpaisan, Sumalee; Vanichtanankul, Jarunee; Thebtaranonth, Yodhathai; Yuthavong, Yongyuth Journal of Medicinal Chemistry, 2002 , vol. 45, # 6 p. 1244 - 1252

186581-53-3 4468-48-8 ~% 18588-50-6

文献：Russell; Hitchings Journal of the American Chemical Society, 1951 , vol. 73, p. 3763,3766

22211-32-1 113-00-8 ~% 18588-50-6

文献：Tarnchompoo, Bongkoch; Sirichaiwat, Chawanee; Phupong, Worrapong; Intaraudom, Chakapong; Sirawaraporn, Worachart; Kamchonwongpaisan, Sumalee; Vanichtanankul, Jarunee; Thebtaranonth, Yodhathai; Yuthavong, Yongyuth Journal of Medicinal Chemistry, 2002 , vol. 45, # 6 p. 1244 - 1252

4468-48-8 ~% 18588-50-6

文献：Chase; Walker Journal of the Chemical Society, 1953 , p. 3518,3523

上下游产品

上游产品  5
140-29-4 186581-53-3 4468-48-8 22211-32-1
113-00-8
下游产品  0

海关

海关编码	2933599090
中文概述	2933599090. 其他结构上有嘧啶环的化合物(包括其他结构上有哌嗪环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%