128449-51-4

• 常用中文名：N-acetyllactosaminide 3-α-galactosyltransferase
• 常用英文名：N-acetyllactosaminide 3-α-galactosyltransferase
• CAS号：128449-51-4
• 分子式：
• 分子量：
• 相关类别： 研究领域 代谢疾病
• 发布时间：2020-04-07 18:27:56
• 更新时间：2025-08-22 12:52:57
• 作用于β-半乳糖基-1,4-N-乙酰氨基葡萄糖基末端的asialo-α1-酸性糖蛋白和N-乙酰乳糖胺(β-D-半乳糖基-1,4-N-乙酰-β-D-葡萄糖胺),但不作用于2'-岩藻糖基-N-乙酰乳糖胺。糖蛋白的非还原末端N-乙酰乳糖胺残基也可以作为受体。现在包括酶代码EC2.4.1.124和EC2.4.1.151。 反应：UDP-α-D-galactose + β-D-galactosyl-(1→4)-β-N-acetyl-D-glucosaminyl-R = UDP + α-D-galactosyl-(1→3)-β-D-galactosyl-(1→4)-β-N-acetylglucosaminyl-R (where R can be OH, an oligosaccharide or a glycoconjugate)

名称

• 英文名: N-acetyllactosaminide 3-α-galactosyltransferase
• 英文别名: EC 2.4.1.87; α-galactosyltransferase; UDP-Gal:β-D-Gal(1,4)-D-GlcNAc α(1,3)-galactosyltransferase; UDP-Gal:N-acetyllactosaminide α(1,3)-galactosyltransferase; UDP-Gal:N-acetyllactosaminide α-1,3-D-galactosyltransferase; UDP-Gal:Galβ1→4GlcNAc-R α1→3-galactosyltransferase; UDP-galactose-acetyllactosamine α-D-galactosyltransferase; UDPgalactose:β-D-galactosyl-β-1,4-N-acetyl-D-glucosaminyl-glycopeptide α-1,3-D-galactosyltransferase; glucosaminylglycopeptide α-1,3-galactosyltransferase; uridine diphosphogalactose-acetyllactosamine α1→3-galactosyltransferase; uridine diphosphogalactose-acetyllactosamine galactosyltransferase; uridine diphosphogalactose-galactosylacetylglucosaminylgalactosylglucosylceramide galactosyltransferase; β-D-galactosyl-N-acetylglucosaminylglycopeptide α-1,3-galactosyltransferase; UDP-galactose:N-acetyllactosaminide 3-α-D-galactosyltransferase; UDP-galactose:β-D-galactosyl-1,4-β-N-acetyl-D-glucosaminyl-R 3-α-D-galactosyltransferase; UDP-galactose:β-D-galactosyl-(1→4)-β-N-acetyl-D-glucosaminyl-R 3-α-D-galactosyltransferase

物化性质

暂时没有任何物化性质资料

生物活性

• 描述: 作用于β-半乳糖基-1,4-N-乙酰氨基葡萄糖基末端的asialo-α1-酸性糖蛋白和N-乙酰乳糖胺(β-D-半乳糖基-1,4-N-乙酰-β-D-葡萄糖胺),但不作用于2'-岩藻糖基-N-乙酰乳糖胺。糖蛋白的非还原末端N-乙酰乳糖胺残基也可以作为受体。现在包括酶代码EC2.4.1.124和EC2.4.1.151。 反应：UDP-α-D-galactose + β-D-galactosyl-(1→4)-β-N-acetyl-D-glucosaminyl-R = UDP + α-D-galactosyl-(1→3)-β-D-galactosyl-(1→4)-β-N-acetylglucosaminyl-R (where R can be OH, an oligosaccharide or a glycoconjugate)