261956-22-3

• 常用中文名：5-[1,1'-联苯]-4-基-5-[4-(4-硝基苯基)-1-哌嗪基]-2,4,6-(1H,3H,5H)-嘧啶三酮
• 常用英文名：RO 28-2653
• CAS号：261956-22-3
• 分子式：C₂₆H₂₃N₅O₅
• 分子量：485.491
• 发布时间：2018-06-23 00:36:54
• 更新时间：2025-08-29 11:42:25
• RO 28-2653 is a potent, selective and orally active matrix-metalloproteinases (MMPs) MMP2, MMP9 and MMP14 inhibitor with IC50 of 10, 12 and 10 nM, shows no activity against MMP3 and MMP1 (IC50>1 uM).

名称

• 中文名: 5-[1,1'-联苯]-4-基-5-[4-(4-硝基苯基)-1-哌嗪基]-2,4,6-(1H,3H,5H)-嘧啶三酮
• 英文名: 5-(4-Biphenylyl)-5-[4-(4-nitrophenyl)-1-piperazinyl]-2,4,6(1H,3H,5H)-pyrimidinetrione
• 英文别名: 5-(4-Biphenylyl)-5-[4-(4-nitrophenyl)-1-piperazinyl]-2,4,6(1H,3H,5H)-pyrimidinetrione; 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-[1,1'-biphenyl]-4-yl-5-[4-(4-nitrophenyl)-1-piperazinyl]-; RO 28-2653

物化性质

• 密度: 1.4±0.1 g/cm3
• 分子式: C₂₆H₂₃N₅O₅
• 分子量: 485.491
• 精确质量: 485.169922
• LogP: 5.28
• 折射率: 1.649
• 储存条件: 2-8°C