97677-73-1

• 常用中文名：5-羟基-5H-茚并[1,2-b]吡啶-5-羧酸甲酯
• 常用英文名：methyl 5-hydroxyindeno[1,2-b]pyridine-5-carboxylate
• CAS号：97677-73-1
• 分子式：C₁₄H₁₁NO₃
• 分子量：241.24200
• 发布时间：2018-12-30 21:21:26
• 更新时间：2025-08-27 20:38:03

名称

• 中文名: 5-羟基-5H-茚并[1,2-b]吡啶-5-羧酸甲酯
• 英文名: methyl 5-hydroxyindeno[1,2-b]pyridine-5-carboxylate
• 英文别名: 5H-Indeno[1,2-b]pyridine-5-carboxylic acid,5-hydroxy-,methyl ester; 4-aza-9-hydroxy-9-fluorene carboxylic acid methyl ester; (RS)-methyl 5H-5-hydroxyindeno<1,2-b>pyridine-5-carboxylate; 5-hydroxy-5H-indeno[1,2-b]pyridine-5-carboxylic acid methyl ester; 4-aza-9-hydroxyfluorene-9-carboxylic acid methyl ester

物化性质

• 分子式: C₁₄H₁₁NO₃
• 分子量: 241.24200
• 精确质量: 241.07400
• PSA: 59.42000
• LogP: 1.47090

合成路线

244-99-5 75-36-5 ~83% 97677-73-1

文献：Alcon Laboratories, Inc. Patent: US4537892 A1, 1985 ;

6602-54-6 ~% 97677-73-1

文献：Stauffer, Kenneth J.; Williams, Peter D.; Selnick, Harold G.; Nantermet, Philippe G.; Newton, Christina L.; Homnick, Carl F.; Zrada, Matthew M.; Lewis, S. Dale; Lucas, Bobby J.; Krueger, Julie A.; Pietrak, Beth L.; Lyle, Elizabeth A.; Singh, Rominder; Miller-Stein, Cynthia; White, Rebecca B.; Wong, Bradley; Wallace, Audrey A.; Sitko, Gary R.; Cook, Jacquelyn J.; Holahan, Marie A.; Stranieri-Michener, Maria; Leonard, Yvonne M.; Lynch Jr., Joseph J.; McMasters, Daniel R.; Yan, Youwei Journal of Medicinal Chemistry, 2005 , vol. 48, # 7 p. 2282 - 2293

3882-46-0 ~% 97677-73-1

文献：Stauffer, Kenneth J.; Williams, Peter D.; Selnick, Harold G.; Nantermet, Philippe G.; Newton, Christina L.; Homnick, Carl F.; Zrada, Matthew M.; Lewis, S. Dale; Lucas, Bobby J.; Krueger, Julie A.; Pietrak, Beth L.; Lyle, Elizabeth A.; Singh, Rominder; Miller-Stein, Cynthia; White, Rebecca B.; Wong, Bradley; Wallace, Audrey A.; Sitko, Gary R.; Cook, Jacquelyn J.; Holahan, Marie A.; Stranieri-Michener, Maria; Leonard, Yvonne M.; Lynch Jr., Joseph J.; McMasters, Daniel R.; Yan, Youwei Journal of Medicinal Chemistry, 2005 , vol. 48, # 7 p. 2282 - 2293

33421-39-5 ~% 97677-73-1

文献：Stauffer, Kenneth J.; Williams, Peter D.; Selnick, Harold G.; Nantermet, Philippe G.; Newton, Christina L.; Homnick, Carl F.; Zrada, Matthew M.; Lewis, S. Dale; Lucas, Bobby J.; Krueger, Julie A.; Pietrak, Beth L.; Lyle, Elizabeth A.; Singh, Rominder; Miller-Stein, Cynthia; White, Rebecca B.; Wong, Bradley; Wallace, Audrey A.; Sitko, Gary R.; Cook, Jacquelyn J.; Holahan, Marie A.; Stranieri-Michener, Maria; Leonard, Yvonne M.; Lynch Jr., Joseph J.; McMasters, Daniel R.; Yan, Youwei Journal of Medicinal Chemistry, 2005 , vol. 48, # 7 p. 2282 - 2293

39065-49-1 ~% 97677-73-1

文献：Stauffer, Kenneth J.; Williams, Peter D.; Selnick, Harold G.; Nantermet, Philippe G.; Newton, Christina L.; Homnick, Carl F.; Zrada, Matthew M.; Lewis, S. Dale; Lucas, Bobby J.; Krueger, Julie A.; Pietrak, Beth L.; Lyle, Elizabeth A.; Singh, Rominder; Miller-Stein, Cynthia; White, Rebecca B.; Wong, Bradley; Wallace, Audrey A.; Sitko, Gary R.; Cook, Jacquelyn J.; Holahan, Marie A.; Stranieri-Michener, Maria; Leonard, Yvonne M.; Lynch Jr., Joseph J.; McMasters, Daniel R.; Yan, Youwei Journal of Medicinal Chemistry, 2005 , vol. 48, # 7 p. 2282 - 2293

98-80-6 ~% 97677-73-1

文献：Stauffer, Kenneth J.; Williams, Peter D.; Selnick, Harold G.; Nantermet, Philippe G.; Newton, Christina L.; Homnick, Carl F.; Zrada, Matthew M.; Lewis, S. Dale; Lucas, Bobby J.; Krueger, Julie A.; Pietrak, Beth L.; Lyle, Elizabeth A.; Singh, Rominder; Miller-Stein, Cynthia; White, Rebecca B.; Wong, Bradley; Wallace, Audrey A.; Sitko, Gary R.; Cook, Jacquelyn J.; Holahan, Marie A.; Stranieri-Michener, Maria; Leonard, Yvonne M.; Lynch Jr., Joseph J.; McMasters, Daniel R.; Yan, Youwei Journal of Medicinal Chemistry, 2005 , vol. 48, # 7 p. 2282 - 2293

439118-19-1 67-56-1 ~% 97677-73-1

文献：Stauffer, Kenneth J.; Williams, Peter D.; Selnick, Harold G.; Nantermet, Philippe G.; Newton, Christina L.; Homnick, Carl F.; Zrada, Matthew M.; Lewis, S. Dale; Lucas, Bobby J.; Krueger, Julie A.; Pietrak, Beth L.; Lyle, Elizabeth A.; Singh, Rominder; Miller-Stein, Cynthia; White, Rebecca B.; Wong, Bradley; Wallace, Audrey A.; Sitko, Gary R.; Cook, Jacquelyn J.; Holahan, Marie A.; Stranieri-Michener, Maria; Leonard, Yvonne M.; Lynch Jr., Joseph J.; McMasters, Daniel R.; Yan, Youwei Journal of Medicinal Chemistry, 2005 , vol. 48, # 7 p. 2282 - 2293

97677-72-0 ~% 97677-73-1

文献：Braven, J.; Hanson, R. W.; Smith, N. G. Journal of Heterocyclic Chemistry, 1995 , vol. 32, # 3 p. 1051 - 1056

244-99-5 ~% 97677-73-1

文献：Braven, J.; Hanson, R. W.; Smith, N. G. Journal of Heterocyclic Chemistry, 1995 , vol. 32, # 3 p. 1051 - 1056

上下游产品

上游产品  10
244-99-5 75-36-5 6602-54-6 3882-46-0
33421-39-5 39065-49-1 98-80-6 439118-19-1
67-56-1 97677-72-0
下游产品  0