13657-68-6

• 常用中文名：莪术二酮
• 常用英文名：Curdione
• CAS号：13657-68-6
• 分子式：C₁₅H₂₄O₂
• 分子量：236.350
• 相关类别： 生物化工 植物提取物
• 发布时间：2018-08-26 17:32:14
• 更新时间：2026-07-03 17:27:43
• 莪术二酮 (Curdione)是从莪术中分离到的倍半萜类物质,生物活性高,具有抑制血小板聚集、抵抗血栓形成的功效。

名称

• 中文名: 莪二酮
• 英文名: (3S,6E,10S)-6,10-dimethyl-3-propan-2-ylcyclodec-6-ene-1,4-dione
• 中文别名: 莪术二酮, 来源于莪术; 莪术醇提物; 莪术二酮Curdione; 莪术二酮(姜黄二酮; (3S,10S,E)-3-异丙基-6,10-二甲基环癸烷-6-烯-1,4-二酮; 莪术二酮(对照品); 莪术二酮(分析标准品); 莪术酮姜黄二酮,莪二酮; 莪二酮/莪术二酮; 莪二酮,莪术二酮.姜黄二酮; 莪术二酮/萜类; 姜黄二酮,莪术酮; 莪术二酮(莪二酮; 莪术二酮(莪术酮姜黄二酮; 卡迪酮; 莪二酮(莪术二酮/姜黄二酮); 莪术二酮(莪术酮姜黄二酮,莪二酮); 卡多酮; (3S,6E,10S)-6,10-二甲基-3-异丙基环癸-6-烯-1,4-二酮; 莪术二酮(标准品); 莪二酮对照品; 莪术提取物; 莪术酮姜黄二酮; 姜黄二酮、莪二酮; 莪术二酮 Solbio/索莱宝 IC1570; 姜黄二酮; CURDIONE 莪术二酮
• 英文别名: (3R,6E,10S)-3-Isopropyl-6,10-dimethyl-6-cyclodecene-1,4-dione; Curdione from Curcuma zedoia (Christm.) Rosc; neo-Curdione; curcumae rhizoma P.E; Germacr-1(10)-ene-5,8-dione; AuginousTurmericRhizome; Zedoy turmeric extract; (3S,6E,10S)-6,10-Dimethyl-3-propan-2-ylcyclodec-6-ene-1,4-dione; (+)-Curdione; N1432; Curcuma two ketone; Curcuma Tuber Extract; Ethanol extracts of Rhizoma Zedoiae; (3S,10S,E)-3-Isopropyl-6,10-dimethylcyclodec-6-ene-1,4-dione; Curdione ((+)-Curdione); 6-Cyclodecene-1,4-dione, 6,10-dimethyl-3-(1-methylethyl)-, (3S,6E,10S); 6,10-Dimethyl-3-isopropyl-6-cyclodecene-1,4-dione; (3S,10S)-3-Isopropyl-6,10-dimethyl-6-cyclodecene-1,4-dione

物化性质

• 密度: 0.9±0.1 g/cm3
• 沸点: 347.6±42.0 °C at 760 mmHg
• 分子式: C₁₅H₂₄O₂
• 分子量: 236.350
• 闪点: 130.4±24.9 °C
• 精确质量: 236.177628
• PSA: 34.14000
• LogP: 3.12
• 蒸汽压: 0.0±0.8 mmHg at 25°C
• 折射率: 1.458
• 储存条件: -20°C

生物活性

• 描述: 莪术二酮 (Curdione)是从莪术中分离到的倍半萜类物质,生物活性高,具有抑制血小板聚集、抵抗血栓形成的功效。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 其他
  天然产物 >> 萜类化合物和糖苷
• 参考文献:

  [1]. SI Li, et al. Effect of curdione on hemorheological indexs in rats with blood stasis syndrome. Anhui Medical and Pharmaceutical Journal, 2012-09

  [2]. Quan Xia, et al. Inhibition of platelet aggregation by curdione from Curcuma wenyujin essential Oil. Thrombosis Research Volume 130, Issue 3, September 2012, Pages 409–414

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : LY3960000 CHEMICAL NAME : Germacr-1(10)-ene-5,8-dione CAS REGISTRY NUMBER : 13657-68-6 LAST UPDATED : 199507 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C15-H24-O2 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 414 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 85PEAG "Zhongliu Yanjiu" Cancer Review, Yu, R., et al., eds., Shanghai Science/Technology Publisher, Peop. Rep. China, 1994 Volume(issue)/page/year: -,178,1994

安全

• 海关编码: 29143990