144583-94-8

• 常用中文名：8-amino-1-methyl-4,5-dihydro-3H-1-benzazepin-2-one
• 常用英文名：8-amino-1-methyl-4,5-dihydro-3H-1-benzazepin-2-one
• CAS号：144583-94-8
• 分子式：C₁₁H₁₄N₂O
• 分子量：190.24200
• 发布时间：2016-12-21 17:27:19
• 更新时间：2025-10-02 16:48:38

名称

• 英文名: 8-amino-1-methyl-4,5-dihydro-3H-1-benzazepin-2-one
• 英文别名: 8-amino-2,3,4,5-tetrahydro-1-methyl-2-oxo-1H-1-benzazepine; 8-AMINO-1-METHYL-2,3,4,5-TETRAHYDRO-1H-1-BENZAZEPIN-2-ONE; 8-amino-1-methyl-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one

物化性质

• 分子式: C₁₁H₁₄N₂O
• 分子量: 190.24200
• 精确质量: 190.11100
• PSA: 46.33000
• LogP: 2.21410

合成路线

1022960-15-1 ~58% 144583-94-8

文献：CEPHALON, INC.; PHARMACOPEIA DRUG DISCOVERY, INC. Patent: WO2008/51547 A1, 2008 ; Location in patent: Page/Page column 349 ; WO 2008/051547 A1

144583-93-7 ~% 144583-94-8

文献：SANOFI; CARRY, Jean-Christophe; CHATREAUX, Fabienne; DEPRETS, Stéphanie; DUCLOS, Olivier; LEROY, Vincent; MALLART, Sergio; MELON-MANGUER, Dominique; MENDEZ-PEREZ, Maria; VERGNE, Fabrice Patent: WO2013/150036 A1, 2013 ; Location in patent: Page/Page column 111 ;

529-34-0 ~% 144583-94-8

文献：SANOFI; CARRY, Jean-Christophe; CHATREAUX, Fabienne; DEPRETS, Stéphanie; DUCLOS, Olivier; LEROY, Vincent; MALLART, Sergio; MELON-MANGUER, Dominique; MENDEZ-PEREZ, Maria; VERGNE, Fabrice Patent: WO2013/150036 A1, 2013 ;

40353-34-2 ~% 144583-94-8

文献：SANOFI; CARRY, Jean-Christophe; CHATREAUX, Fabienne; DEPRETS, Stéphanie; DUCLOS, Olivier; LEROY, Vincent; MALLART, Sergio; MELON-MANGUER, Dominique; MENDEZ-PEREZ, Maria; VERGNE, Fabrice Patent: WO2013/150036 A1, 2013 ;

67104-86-3 ~% 144583-94-8

文献：SANOFI; CARRY, Jean-Christophe; CHATREAUX, Fabienne; DEPRETS, Stéphanie; DUCLOS, Olivier; LEROY, Vincent; MALLART, Sergio; MELON-MANGUER, Dominique; MENDEZ-PEREZ, Maria; VERGNE, Fabrice Patent: WO2013/150036 A1, 2013 ;

22246-79-3 ~% 144583-94-8

文献：SANOFI; CARRY, Jean-Christophe; CHATREAUX, Fabienne; DEPRETS, Stéphanie; DUCLOS, Olivier; LEROY, Vincent; MALLART, Sergio; MELON-MANGUER, Dominique; MENDEZ-PEREZ, Maria; VERGNE, Fabrice Patent: WO2013/150036 A1, 2013 ;

上下游产品

上游产品  5
1022960-15-1 529-34-0 40353-34-2 67104-86-3
22246-79-3
下游产品  0