18361-48-3

• 常用中文名：leucomycin A6
• 常用英文名：leucomycin A6
• CAS号：18361-48-3
• 分子式：C₄₀H₆₅NO₁₅
• 分子量：799.94200
• 发布时间：2016-06-22 21:49:57
• 更新时间：2024-01-30 15:48:40

名称

• 英文名: [6-[6-[[(11Z,13E)-4-acetyloxy-10-hydroxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-6-yl]oxy]-4-(dimethylamino)-5-hydroxy-2-methyloxan-3-yl]oxy-4-hydroxy-2,4-dimethyloxan-3-yl] propanoate
• 英文别名: Antibiotic yl-704 B3; Turimycin A3; Platenomycin-B3; Leucomycin V 3-acetate 4b-propanoate; Yl 704 B3; Leucomycin A6; Leukomycin A6

物化性质

• 密度: 1.22g/cm3
• 沸点: 867ºC at 760mmHg
• 分子式: C₄₀H₆₅NO₁₅
• 分子量: 799.94200
• 闪点: 478.1ºC
• 精确质量: 799.43500
• PSA: 206.05000
• LogP: 2.37730
• 蒸汽压: 4.52E-35mmHg at 25°C
• 折射率: 1.537

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : OH4725500 CHEMICAL NAME : Leucomycin A6 CAS REGISTRY NUMBER : 18361-48-3 LAST UPDATED : 199512 DATA ITEMS CITED : 5 MOLECULAR FORMULA : C40-H65-N-O15 MOLECULAR WEIGHT : 800.06 WISWESSER LINE NOTATION : T-16-OV KU MUTJ DOO2 EO1 G1VH I1 JQ P1 FO- BT6OTJ CQ DN1&1 F1 EO- FT6OTJ B1 COV2 DQ D1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 9600 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,810,1982 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 4900 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JJANAX Japanese Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo 141, Japan) V.21- 1968- Volume(issue)/page/year: 37,1565,1984 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 800 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 2,87,1980 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >10 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 4,193,1973 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #3535309