21561-99-9

• 常用中文名：Urea,N-methyl-N-nitroso-N'-phenyl-
• 常用英文名：Urea,N-methyl-N-nitroso-N'-phenyl-
• CAS号：21561-99-9
• 分子式：C₈H₉N₃O₂
• 分子量：179.17600
• 发布时间：2017-05-20 09:55:34
• 更新时间：2025-08-26 21:17:32

名称

• 英文名: 1-methyl-1-nitroso-3-phenylurea
• 英文别名: Methylphenylnitrosourea; 3-Phenyl-1-methyl-1-nitrosoharnstoff; Nitrosomethylphenylurea; N-Methyl-N-nitroso-N'-phenylurea; N-Methyl-N-nitroso-N'-phenyl-harnstoff; MPNU; N-Nitroso-N-methyl-N'-phenylharnstoff; Urea,1-methyl-1-nitroso-3-phenyl; 1-Methyl-1-nitro-3-phenyl-harnstoff; N-methyl-N'-phenyl-N-nitrosourea

物化性质

• 密度: 1.22g/cm3
• 分子式: C₈H₉N₃O₂
• 分子量: 179.17600
• 精确质量: 179.06900
• PSA: 61.77000
• LogP: 1.90470
• 折射率: 1.574

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : YT8100000 CHEMICAL NAME : Urea, 1-methyl-1-nitroso-3-phenyl- CAS REGISTRY NUMBER : 21561-99-9 LAST UPDATED : 199612 DATA ITEMS CITED : 10 MOLECULAR FORMULA : C8-H9-N3-O2 MOLECULAR WEIGHT : 179.20 WISWESSER LINE NOTATION : ONN1&VMR HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 750 mg/kg/32W-I TOXIC EFFECTS : Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 250 mg/kg TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 532 mg/kg/7W-I TOXIC EFFECTS : Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors Skin and Appendages - tumors TYPE OF TEST : TD - Toxic dose (other than lowest) ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 450 mg/kg/20W-I TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors TYPE OF TEST : TD - Toxic dose (other than lowest) ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 650 mg/kg/W-I TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors Liver - tumors TYPE OF TEST : TD - Toxic dose (other than lowest) ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 650 mg/kg/26W-I TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors Liver - tumors TYPE OF TEST : TD - Toxic dose (other than lowest) ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 650 mg/kg/26W-I TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Kidney, Ureter, Bladder - Kidney tumors MUTATION DATA TYPE OF TEST : Sister chromatid exchange TEST SYSTEM : Rodent - hamster Lung DOSE/DURATION : 10 umol/L REFERENCE : IAPUDO IARC Publications. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.27- 1979- Volume(issue)/page/year: 31,797,1980

安全

• 海关编码: 2924299090

合成路线

1007-36-9 ~94% 21561-99-9

文献：Tanno, Masayuki; Sueyoshi, Shoko Chemical & Pharmaceutical Bulletin, 1987 , vol. 35, # 4 p. 1360 - 1371

1007-36-9 ~87% 21561-99-9 110396-87-7

文献：Tanno, Masayuki; Sueyoshi, Shoko Chemical & Pharmaceutical Bulletin, 1987 , vol. 35, # 4 p. 1360 - 1371

74497-02-2 ~% 21561-99-9

文献：Snyder, John K.; Stock, Leon M. Journal of Organic Chemistry, 1980 , vol. 45, # 5 p. 886 - 891

624-83-9 74497-02-2 ~% 21561-99-9

文献：Yoshida, Kitaro; Isobe, Masayoshi; Yano, Kazuyuki; Nagamatsu, Kazuo Bulletin of the Chemical Society of Japan, 1985 , vol. 58, # 7 p. 2143 - 2144

26891-98-5 74497-02-2 ~% 21561-99-9

文献：Hardegger; Meier; Stoos Helvetica chimica acta, 1969 , vol. 52, # 8 p. 2555 - 2560

上下游产品

上游产品  3
1007-36-9 624-83-9 26891-98-5
下游产品  7
17425-13-7 66018-75-5 4910-32-1 56741-08-3
62603-67-2 5628-90-0 102-07-8

海关

海关编码	2924299090
中文概述	2924299090. 其他环酰胺（包括环氨基甲酸酯）（包括其衍生物以及他们的盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 包装
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%