38243-03-7

• 常用中文名：20(R)-人参皂苷Rg3
• 常用英文名：20(R)-Ginsenoside Rg3
• CAS号：38243-03-7
• 分子式：C₄₂H₇₂O₁₃
• 分子量：1079.269
• 相关类别： 研究领域 癌症
• 发布时间：2018-08-26 13:28:11
• 更新时间：2024-01-04 09:04:37
• 20(R)-ginsenoside Rg3 (20(R)-Propanaxadiol),人参根中的一种活性化合物,具有有效的血管抑制活性和抗肿瘤活性。

名称

• 中文名: 人参皂甙 Rg3
• 英文名: 20(R)-Propanaxadiol
• 中文别名: 20(R)人参皂苷Rg3; 人参皂苷 R-RG3; (R型)人参皂苷Rg3; 人参皂苷 Rg3; R-人参皂苷 Rg3; 20(R)人参皂甙Rg3; R型人参皂苷Rg3
• 英文别名: 20(S)-ginsenoside Rg3; (3β,12β)-20-{[2-O-(β-D-Glucopyranosyl)-β-D-glucopyranosyl]oxy}-12-hydroxydammar-24-en-3-yl 6-O-β-D-xylopyranosyl-α-D-glucopyranoside; Ginsenoside Rg3 (R-); α-D-Glucopyranoside, (3β,12β)-20-[(2-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-12-hydroxydammar-24-en-3-yl 6-O-β-D-xylopyranosyl-; Ginsenoside Rg3 Rh2; 20(R)Ginsenoside Rg3; R-form-Ginsenoside Rg3; GINSENOSIDE RG3(R-FORM)(P); (2S,3R,4S,5S,6R)-2-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-2-[[(10R,12S,13R,14R,17S)-12-hydroxy-17-[(2R)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,10,13,14-pentamethyl-2,3,5,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol; (2S,3R,4S,5S,6R)-2-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-2-[[(10R,12S,13R,14R,17S)-12-hydroxy-17-[(1R)-1-hydroxy-1,5-dimethyl-hex-4-enyl]-4,4,10,13,14-pentamethyl-2,3,5,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-methylol-tetrahydropyran-3-yl]oxy-6-methylol-tetrahydropyran-3,4,5-triol; Ginsenoside Rg3; 20(R)-Ginsenoside-Rg3

物化性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 1117.1±65.0 °C at 760 mmHg
• 熔点: 315-318ºC
• 分子式: C₄₂H₇₂O₁₃
• 分子量: 1079.269
• 闪点: 629.4±34.3 °C
• 精确质量: 1078.592407
• PSA: 357.06000
• LogP: 4.73
• 外观性状: 固体;White to Light yellow powder to crystal
• 蒸汽压: 0.0±0.6 mmHg at 25°C
• 折射率: 1.622
• 储存条件: 0-10°C;避免加热

生物活性

• 描述: 20(R)-ginsenoside Rg3 (20(R)-Propanaxadiol),人参根中的一种活性化合物,具有有效的血管抑制活性和抗肿瘤活性。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Liu L, et al. Enzymatic preparation of 20(S, R)-protopanaxadiol by transformation of 20(S, R)-Rg3 from blackginseng. Phytochemistry. 2010 Sep;71(13):1514-20.

  [2]. Yue PY, et al. The angiosuppressive effects of 20(R)- ginsenoside Rg3. Biochem Pharmacol. 2006 Aug 14;72(4):437-45.