331977-03-8

• 常用中文名：1-(3-溴苯甲基)-4-甲基哌嗪
• 常用英文名：1-(3-Bromobenzyl)-4-methylpiperazine
• CAS号：331977-03-8
• 分子式：C₁₂H₁₇BrN₂
• 分子量：269.181
• 发布时间：2018-12-25 08:46:27
• 更新时间：2024-04-05 17:44:19

名称

• 中文名: 1-(3-溴苯甲基)-4-甲基哌嗪
• 英文名: 1-(3-Bromobenzyl)-4-methylpiperazine
• 英文别名: Piperazine, 1-[(3-bromophenyl)methyl]-4-methyl-; 1-(3-Bromobenzyl)-4-methylpiperazine; 1-[(3-BROMOPHENYL)METHYL]-4-METHYLPIPERAZINE; 1-(3-bromo-benzyl)-4-methyl-piperazine

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 325.3±27.0 °C at 760 mmHg
• 分子式: C₁₂H₁₇BrN₂
• 分子量: 269.181
• 闪点: 150.5±23.7 °C
• 精确质量: 268.057495
• PSA: 6.48000
• LogP: 1.69
• 蒸汽压: 0.0±0.7 mmHg at 25°C
• 折射率: 1.575

安全

• 海关编码: 2933599090

合成路线

109-01-3 823-78-9 ~% 331977-03-8

文献：F. HOFFMANN-LA ROCHE AG Patent: WO2008/28617 A1, 2008 ; Location in patent: Page/Page column 44-45 ; WO 2008/028617 A1

109-01-3 3132-99-8 ~66% 331977-03-8

文献：Duffey, Matthew O.; Vos, Tricia J.; Adams, Ruth; Alley, Jennifer; Anthony, Justin; Barrett, Cynthia; Bharathan, Indu; Bowman, Douglas; Bump, Nancy J.; Chau, Ryan; Cullis, Courtney; Driscoll, Denise L.; Elder, Amy; Forsyth, Nancy; Frazer, Jonathan; Guo, Jianping; Guo, Luyi; Hyer, Marc L.; Janowick, David; Kulkarni, Bheemashankar; Lai, Su-Jen; Lasky, Kerri; Li, Gang; Li, Jing; Liao, Debra; Little, Jeremy; Peng, Bo; Qian, Mark G.; Reynolds, Dominic J.; Rezaei, Mansoureh; Scott, Margaret Porter; Sells, Todd B.; Shinde, Vaishali; Shi, Qiuju Judy; Sintchak, Michael D.; Soucy, Francois; Sprott, Kevin T.; Stroud, Stephen G.; Nestor, Michelle; Visiers, Irache; Weatherhead, Gabriel; Ye, Yingchun; Damore, Natalie Journal of Medicinal Chemistry, 2012 , vol. 55, # 1 p. 197 - 208

海关

海关编码	2933599090
中文概述	2933599090. 其他结构上有嘧啶环的化合物(包括其他结构上有哌嗪环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%