917758-91-9

• 常用中文名：6-(4-氟苯基)吡啶并[3,2-d]嘧啶-2,4-二醇
• 常用英文名：6-(4-fluorophenyl)-1H-pyrido[3,2-d]pyrimidine-2,4-dione
• CAS号：917758-91-9
• 分子式：C₁₃H₈FN₃O₂
• 分子量：257.22000
• 发布时间：2018-12-25 19:15:54
• 更新时间：2024-01-05 15:01:21

名称

• 中文名: 6-(4-氟苯基)吡啶并[3,2-d]嘧啶-2,4-二醇
• 英文名: 6-(4-fluorophenyl)-1H-pyrido[3,2-d]pyrimidine-2,4-dione
• 英文别名: 6-(4-fluorophenyl)pyrido[3,2-d]pyrimidine-2,4-diol

物化性质

• 分子式: C₁₃H₈FN₃O₂
• 分子量: 257.22000
• 精确质量: 257.06000
• PSA: 79.13000
• LogP: 2.24210

合成路线

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文献：GILEAD SCIENCES, INC. Patent: WO2008/77651 A1, 2008 ; Location in patent: Page/Page column 55-56 ;

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文献：Lazerwith, Scott E.; Bahador, Gina; Canales, Eda; Cheng, Guofeng; Chong, Lee; Clarke, Michael O.; Doerffler, Edward; Eisenberg, Eugene J.; Hayes, Jaclyn; Lu, Bing; Liu, Qi; Matles, Mike; Mertzman, Michael; Mitchell, Michael L.; Morganelli, Philip; Murray, Bernard P.; Robinson, Margaret; Strickley, Robert G.; Tessler, Megan; Tirunagari, Neeraj; Wang, Jianhong; Wang, Yujin; Zhang, Jennifer R.; Zheng, Xubin; Zhong, Weidong; Watkins, William J. ACS Medicinal Chemistry Letters, 2011 , vol. 2, # 10 p. 715 - 719

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文献：Lazerwith, Scott E.; Bahador, Gina; Canales, Eda; Cheng, Guofeng; Chong, Lee; Clarke, Michael O.; Doerffler, Edward; Eisenberg, Eugene J.; Hayes, Jaclyn; Lu, Bing; Liu, Qi; Matles, Mike; Mertzman, Michael; Mitchell, Michael L.; Morganelli, Philip; Murray, Bernard P.; Robinson, Margaret; Strickley, Robert G.; Tessler, Megan; Tirunagari, Neeraj; Wang, Jianhong; Wang, Yujin; Zhang, Jennifer R.; Zheng, Xubin; Zhong, Weidong; Watkins, William J. ACS Medicinal Chemistry Letters, 2011 , vol. 2, # 10 p. 715 - 719