216661-57-3

• 常用中文名：VEGFR2激酶抑制剂IV
• 常用英文名：6-(4-methoxyphenyl)-3-thiophen-3-ylpyrazolo[1,5-a]pyrimidine
• CAS号：216661-57-3
• 分子式：C₁₇H₁₃N₃OS
• 分子量：307.37000
• 发布时间：2017-09-29 15:09:08
• 更新时间：2024-01-12 16:06:08

名称

• 中文名: VEGFR2激酶抑制剂IV
• 英文名: 6-(4-methoxyphenyl)-3-thiophen-3-ylpyrazolo[1,5-a]pyrimidine
• 英文别名: VEGF Receptor 2 Kinase Inhibitor IV; HMS3229O15; KDR/Flk-1 Kinase Inhibitor IV

物化性质

• 分子式: C₁₇H₁₃N₃OS
• 分子量: 307.37000
• 精确质量: 307.07800
• PSA: 67.66000
• LogP: 4.13340

合成路线

13781-53-8 ~% 216661-57-3

文献：Fraley, Mark E; Rubino, Robert S; Hoffman, William F; Hambaugh, Scott R; Arrington, Kenneth L; Hungate, Randall W; Bilodeau, Mark T; Tebben, Andrew J; Rutledge, Ruth Z; Kendall, Richard L; McFall, Rosemary C; Huckle, William R; Coll, Kathleen E; Thomas, Kenneth A Bioorganic and medicinal chemistry letters, 2002 , vol. 12, # 24 p. 3537 - 3541

53868-40-9 ~% 216661-57-3

文献：Fraley, Mark E.; Hoffman, William F.; Rubino, Robert S.; Hungate, Randall W.; Tebben, Andrew J.; Rutledge, Ruth Z.; McFall, Rosemary C.; Huckle, William R.; Kendall, Richard L.; Coll, Kathleen E.; Thomas, Kenneth A. Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 19 p. 2767 - 2770

6165-69-1 216661-83-5 ~% 216661-57-3

文献：Fraley, Mark E.; Hoffman, William F.; Rubino, Robert S.; Hungate, Randall W.; Tebben, Andrew J.; Rutledge, Ruth Z.; McFall, Rosemary C.; Huckle, William R.; Kendall, Richard L.; Coll, Kathleen E.; Thomas, Kenneth A. Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 19 p. 2767 - 2770

53868-40-9 162286-51-3 ~% 216661-57-3

文献：Fraley, Mark E; Rubino, Robert S; Hoffman, William F; Hambaugh, Scott R; Arrington, Kenneth L; Hungate, Randall W; Bilodeau, Mark T; Tebben, Andrew J; Rutledge, Ruth Z; Kendall, Richard L; McFall, Rosemary C; Huckle, William R; Coll, Kathleen E; Thomas, Kenneth A Bioorganic and medicinal chemistry letters, 2002 , vol. 12, # 24 p. 3537 - 3541