16413-75-5

• 常用中文名：N-(beta-羟基-alpha-甲基苯乙基)-N-甲基-乙酰胺
• 常用英文名：N-(β-Hydroxy-α-methylphenethyl)-N-methylacetamide
• CAS号：16413-75-5
• 分子式：C₁₂H₁₇NO₂
• 分子量：207.26900
• 发布时间：2018-12-15 07:44:27
• 更新时间：2025-08-25 10:48:08

名称

• 中文名: N-(beta-羟基-alpha-甲基苯乙基)-N-甲基-乙酰胺
• 英文名: N-(1-hydroxy-1-phenylpropan-2-yl)-N-methylacetamide
• 英文别名: N-Acetylpseudoephedrine; N-(2-Hydroxy-1-methyl-2-phenyl-aethyl)-N-methyl-acetamid; N-(2-hydroxy-1-methyl-2-phenyl-ethyl)-N-methyl-acetamide; 1-(Phenyl)-2-(N-methyl-N-acetylamino)-1-propanol; N-Acetylephedrine; N-acetyl-N-methylnorephedrine; N-Acetyl-(d-pseudoephedrin)

物化性质

• 密度: 1.083g/cm3
• 沸点: 361.2ºC at 760mmHg
• 分子式: C₁₂H₁₇NO₂
• 分子量: 207.26900
• 闪点: 172.3ºC
• 精确质量: 207.12600
• PSA: 40.54000
• LogP: 1.58680
• 蒸汽压: 7.53E-06mmHg at 25°C
• 折射率: 1.535

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : AC3660000 CHEMICAL NAME : Acetamide, N-(beta-hydroxy-alpha-methylphenethyl)-N-methyl- CAS REGISTRY NUMBER : 16413-75-5 LAST UPDATED : 199012 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C12-H17-N-O2 MOLECULAR WEIGHT : 207.30 WISWESSER LINE NOTATION : 1YR&YQN1&V1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 294 mg/kg TOXIC EFFECTS : Behavioral - changes in motor activity (specific assay) Cardiac - pulse rate increase, without fall in BP Skin and Appendages - hair REFERENCE : APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 38,474,1976

安全

• 海关编码: 2924299090

合成路线

63991-26-4 108-24-7 ~76% 16413-75-5

文献：Zhestkov, V. P.; Voronin, V. G.; Portnov, Yu. N. Pharmaceutical Chemistry Journal, 1983 , vol. 17, # 9 p. 657 - 660 Khimiko-Farmatsevticheskii Zhurnal, 1983 , vol. 17, # 9 p. 1090 - 1093

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海关

海关编码	2924299090
中文概述	2924299090. 其他环酰胺（包括环氨基甲酸酯）（包括其衍生物以及他们的盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 包装
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%