697762-60-0

• 常用中文名：7-氟-1,4-二氢-1-[(1S)-1-(羟基甲基)-2-甲基丙基]-6-碘-4-氧代-3-喹啉甲酸乙酯
• 常用英文名：(S)-7-Fluoro-1-(1-hydroxymethyl-2-methyl-propyl)-6-iodo-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid
• CAS号：697762-60-0
• 分子式：C₁₇H₁₉FINO₄
• 分子量：447.24000
• 发布时间：2018-12-29 12:29:19
• 更新时间：2025-08-26 16:15:22

名称

• 中文名: 7-氟-1,4-二氢-1-[(1S)-1-(羟基甲基)-2-甲基丙基]-6-碘-4-氧代-3-喹啉甲酸乙酯
• 英文名: (S)-Ethyl 7-fluoro-1-(1-hydroxy-3-methylbutan-2-yl)-6-iodo-4-oxo-1,4-dihydroquinoline-3-carboxylate
• 英文别名: ethyl 7-fluoro-1-[(2S)-1-hydroxy-3-methylbutan-2-yl]-6-iodo-4-oxoquinoline-3-carboxylate

物化性质

• 分子式: C₁₇H₁₉FINO₄
• 分子量: 447.24000
• 精确质量: 447.03400
• PSA: 68.53000
• LogP: 3.11130
• 储存条件: 2-8°C， 密封， 干燥

安全

• 海关编码: 2933499090

合成路线

697762-59-7 ~82% 697762-60-0

文献：SATOH, Motohide; Aramaki, Hisateru; Yamashita, Masaki; Inoue, Masafumi; Kawakami, Hiroshi; Shinkai, Hisashi; Nakamura, Hiroshi; Matsuzaki, Yuji; Wamaki, Shuichi Patent: US2008/207618 A1, 2008 ; Location in patent: Page/Page column 33-34 ;

1131640-54-4 ~85% 697762-60-0

文献：CONCERT PHARMACEUTICALS, INC. Patent: WO2009/35662 A1, 2009 ; Location in patent: Page/Page column 21-24 ;

697762-39-3 2026-48-4 ~77% 697762-60-0

文献：JAPAN TOBACCO INC. Patent: WO2005/113508 A1, 2005 ; Location in patent: Page/Page column 13-14; 19; 24-25; 47 ;

697762-39-3 ~94% 697762-60-0

文献：JAPAN TOBACCO INC. Patent: WO2005/113508 A1, 2005 ; Location in patent: Page/Page column 42 ;

2026-48-4 ~% 697762-60-0

文献：Sato, Motohide; Motomura, Takahisa; Aramaki, Hisateru; Matsuda, Takashi; Yamashita, Masaki; Ito, Yoshiharu; Kawakami, Hiroshi; Matsuzaki, Yuji; Watanabe, Wataru; Yamataka, Kazunobu; Ikeda, Satoru; Kodama, Eiichi; Matsuoka, Masao; Shinkai, Hisashi Journal of Medicinal Chemistry, 2006 , vol. 49, # 5 p. 1506 - 1508

1583-58-0 ~% 697762-60-0

文献：MATRIX LABORATORIES LTD; VELLANKI, Siva, Rama, Prasad; DHAKE, Vilas, Nathu; RAVI, Satyanarayana; NUCHU, Ravi; PULIYALA, Ravindra; SHAIK, Mahaboob, Basha; DATTA, Debashish Patent: WO2011/4389 A2, 2011 ;

72-18-4 ~% 697762-60-0

文献：MATRIX LABORATORIES LTD; VELLANKI, Siva, Rama, Prasad; DHAKE, Vilas, Nathu; RAVI, Satyanarayana; NUCHU, Ravi; PULIYALA, Ravindra; SHAIK, Mahaboob, Basha; DATTA, Debashish Patent: WO2011/4389 A2, 2011 ;

上下游产品

上游产品  5
1131640-54-4 697762-39-3 2026-48-4 1583-58-0
72-18-4
下游产品  0

海关

海关编码	2933499090
中文概述	2933499090. 其他含喹琳或异喹啉环系的化合物〔但未进一步稠合的〕. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%