CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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TP2494900
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CHEMICAL NAME :
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Platinum(II), dichloro(4,5-dimethyl-o-phenylenediammine)-, (SP-4-2)-
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CAS REGISTRY NUMBER :
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40580-75-4
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LAST UPDATED :
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199410
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DATA ITEMS CITED :
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2
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MOLECULAR FORMULA :
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C8-H12-Cl2-N2-Pt
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MOLECULAR WEIGHT :
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402.21
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WISWESSER LINE NOTATION :
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ZR BZ D1 E1 &G-PT-G
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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283 mg/kg
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TOXIC EFFECTS :
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Kidney, Ureter, Bladder - other changes Tumorigenic - active as anti-cancer agent
MUTATION DATA
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TYPE OF TEST :
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Mutation in microorganisms
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TEST SYSTEM :
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Bacteria - Salmonella typhimurium
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DOSE/DURATION :
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10200 nmol/L
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REFERENCE :
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JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 23,459,1980
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