72286-34-1

• 常用中文名：Tetrahydro-2-phenyl-4H-1,3-thiazin-4-one
• 常用英文名：Tetrahydro-2-phenyl-4H-1,3-thiazin-4-one
• CAS号：72286-34-1
• 分子式：C₁₀H₁₁NOS
• 分子量：193.26500
• 发布时间：2016-07-13 07:05:21
• 更新时间：2024-01-08 19:20:51

名称

• 英文名: 2-phenyl-1,3-thiazinan-4-one
• 英文别名: 2-Phenyl-tetrahydro-[1,3]thiazin-4-on; 2-phenyl-tetrahydro-[1,3]thiazin-4-one; (2H)1,3-Oxazine,tetrahydro-2-phenyl; 1,3-Oxazine,tetrahydro-2-phenyl; 2-phenylperhydro-1,3-oxazine; 2-Phenyl-tetrahydro-[1,3]oxazin; 2-phenyl-[1,3]thiazinan-4-one; 2-phenyl-tetrahydro-(2H)-1,3-oxazine; 2-phenyl-tetrahydro-[1,3]oxazine; tetrahydro-2-phenyl-4H-1,3-thiazin-4-one

物化性质

• 分子式: C₁₀H₁₁NOS
• 分子量: 193.26500
• 精确质量: 193.05600
• PSA: 54.40000
• LogP: 2.26710

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : XJ1261700 CHEMICAL NAME : 4H-1,3-Thiazin-4-one, tetrahydro-2-phenyl- CAS REGISTRY NUMBER : 72286-34-1 BEILSTEIN REFERENCE NO. : 0149651 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C10-H11-N-O-S MOLECULAR WEIGHT : 193.28 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >2 gm/kg TOXIC EFFECTS : Vascular - BP lowering not characterized in autonomic section REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 122,517,1957 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1500 mg/kg TOXIC EFFECTS : Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - ataxia Vascular - BP lowering not characterized in autonomic section REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 122,517,1957

合成路线

100-52-7 107-96-0 ~% 72286-34-1

文献：Surrey et al. Journal of the American Chemical Society, 1958 , vol. 80, p. 3469

763-35-9 100-52-7 ~% 72286-34-1

文献：Nyitrai,J. et al. Tetrahedron, 1978 , vol. 34, p. 1031 - 1035

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