87626-55-9

• 常用中文名：米托拉酮
• 常用英文名：mitoflaxone
• CAS号：87626-55-9
• 分子式：C₁₇H₁₂O₄
• 分子量：280.275
• 发布时间：2018-07-12 09:55:52
• 更新时间：2024-01-08 14:11:26

名称

• 中文名: 米托拉酮
• 英文名: 2-(4-oxo-2-phenylchromen-8-yl)acetic acid
• 英文别名: (4-Oxo-2-phenyl-4H-chromen-8-yl)acetic acid; (2-phenyl-4-oxo-4H-1-benzopyran-8-yl)acetic acid; flavone 8-acetic acid; 4H-1-Benzopyran-8-acetic acid, 4-oxo-2-phenyl-; mitoflaxone; LM-975; Flavone acetic acid; Mitoflaxona [INN-Spanish]; Mitoflaxonum [INN-Latin]

物化性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 507.9±50.0 °C at 760 mmHg
• 分子式: C₁₇H₁₂O₄
• 分子量: 280.275
• 闪点: 192.8±23.6 °C
• 精确质量: 280.073547
• PSA: 67.51000
• LogP: 2.84
• 蒸汽压: 0.0±1.4 mmHg at 25°C
• 折射率: 1.649

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : DJ2106000 CHEMICAL NAME : 4H-1-Benzopyran-8-acetic acid, 4-oxo-2-phenyl- CAS REGISTRY NUMBER : 87626-55-9 LAST UPDATED : 199612 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C17-H12-O4 MOLECULAR WEIGHT : 280.29 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 350 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 280 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 392 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value MUTATION DATA TEST SYSTEM : Rodent - mouse DOSE/DURATION : 200 mg/kg REFERENCE : CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 48,1279,1988

安全

• 海关编码: 2918300090

合成路线

181428-95-5 ~76% 87626-55-9

文献：Loewe, Werner; Matzanke, Norbert Journal of Heterocyclic Chemistry, 1996 , vol. 33, # 3 p. 943 - 948

87626-54-8 ~86% 87626-55-9

文献：Atassi; Briet; Berthelon; Collonges European Journal of Medicinal Chemistry, 1985 , vol. 20, # 5 p. 393 - 402

4047-76-1 ~49% 87626-55-9

文献：Aitken, R. Alan; Bibby, Michael C.; Double, John A.; Laws, Andrea L.; Ritchie, Robert B.; Wilson, David W. J. Archiv der Pharmazie, 1997 , vol. 330, # 7 p. 215 - 224

87165-52-4 ~% 87626-55-9

文献：Atassi; Briet; Berthelon; Collonges European Journal of Medicinal Chemistry, 1985 , vol. 20, # 5 p. 393 - 402

上下游产品

上游产品  2
87626-54-8 87165-52-4
下游产品  4
87626-57-1 87626-60-6 87626-65-1 87626-66-2

海关

海关编码	2918300090
中文概述	2918300090 其他含醛基或酮基不含其他含氧基羧酸（包括酸酐、酰卤化物、过氧化物和过氧酸及该税号的衍生物）. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%