75319-92-5

• 常用中文名：3(2H)-Pyridazinone,4-acetyl-5,6-bis(4-chlorophenyl)-2-(2-hydroxyethyl)-
• 常用英文名：3(2H)-Pyridazinone,4-acetyl-5,6-bis(4-chlorophenyl)-2-(2-hydroxyethyl)-
• CAS号：75319-92-5
• 分子式：C₂₀H₁₆Cl₂N₂O₃
• 分子量：403.25900
• 发布时间：2016-12-01 10:51:33
• 更新时间：2024-04-04 20:44:36

名称

• 英文名: 4-acetyl-5,6-bis(4-chlorophenyl)-2-(2-hydroxyethyl)pyridazin-3-one
• 英文别名: 4-acetyl-5,6-bis(4-chlorophenyl)-2-(2-hydroxyethyl)pyridazin-3(2h)-one; 2-(2'-hydroxyethyl)-4-acetyl-5,6-bis(p-chlorophenyl)-2H-pyridazin-3-one; 4-acetyl-5,6-bis(p-chlorophenyl)-2-(2'-hydroxyethyl)-2H-pyridazine-3-one; 4-acetyl-5,6-bis(p-chlorophenyl)-2-(2'-hydroxyethyl)-2H-pyridazin-3-one; 2-(2-hydroxyethyl)pyridazinone; 4-acetyl-2-(2'-hydroxyethyl)-5,6-bis(4-chlorophenyl)-2H-pyridazin-3-one; 3(2H)-Pyridazinone,4-acetyl-5,6-bis(4-chlorophenyl)-2-(2-hydroxyethyl)

物化性质

• 密度: 1.37g/cm3
• 沸点: 582.1ºC at 760 mmHg
• 分子式: C₂₀H₁₆Cl₂N₂O₃
• 分子量: 403.25900
• 闪点: 305.9ºC
• 精确质量: 402.05400
• PSA: 72.19000
• LogP: 4.07900
• 折射率: 1.637

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : UR6114960 CHEMICAL NAME : 3(2H)-Pyridazinone, 4-acetyl-5,6-bis(4-chlorophenyl)-2-(2-hydroxyethyl)- CAS REGISTRY NUMBER : 75319-92-5 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C20-H16-Cl2-N2-O3 MOLECULAR WEIGHT : 403.28 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >300 mg/kg TOXIC EFFECTS : Vascular - BP lowering not characterized in autonomic section REFERENCE : JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 70,419,1981

合成路线

96-49-1 75643-31-1 ~96% 75319-92-5

文献：Powers; Eckert; Gehrlein Journal of Pharmaceutical Sciences, 1981 , vol. 70, # 4 p. 419 - 421

40036-75-7 ~% 75319-92-5

文献：Powers; Eckert; Gehrlein Journal of Pharmaceutical Sciences, 1981 , vol. 70, # 4 p. 419 - 421

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