61630-32-8

• 常用中文名：4-羟基雄烯二酮醋酸酯
• 常用英文名：4-Androsten-4-ol-3,17-dione acetate
• CAS号：61630-32-8
• 分子式：C₂₁H₂₈O₄
• 分子量：344.44500
• 发布时间：2018-09-03 09:54:34
• 更新时间：2024-01-02 12:19:29
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名称

• 中文名: 4-羟基雄烯二酮醋酸酯
• 英文名: 4-Androsten-4-ol-3,17-dione acetate
• 英文别名: [(8R,9S,10R,13S,14S)-10,13-dimethyl-3,17-dioxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-4-yl] acetate

物化性质

• 密度: 1.18g/cm3
• 沸点: 501.2ºC at 760 mmHg
• 分子式: C₂₁H₂₈O₄
• 分子量: 344.44500
• 闪点: 219.2ºC
• 精确质量: 344.19900
• PSA: 60.44000
• LogP: 3.97820
• 折射率: 1.548

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : BV8153000 CHEMICAL NAME : Androst-4-ene-3,17-dione, 4-hydroxy-, acetate (ester) CAS REGISTRY NUMBER : 61630-32-8 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C21-H28-O4 MOLECULAR WEIGHT : 344.49 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intramuscular DOSE : 300 mg/kg SEX/DURATION : female 2-7 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) REFERENCE : BIREBV Biology of Reproduction. (Soc. for the Study of Reproduction, 309 W. Clark St., Champaign, IL 61820) V.1- 1969- Volume(issue)/page/year: 18,365,1978 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Implant DOSE : 375 mg/kg SEX/DURATION : female 18 day(s) pre-mating female 1-8 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - mating performance (e.g. # sperm positive females per # females mated; # copulations per # estrus cycles) REFERENCE : BIREBV Biology of Reproduction. (Soc. for the Study of Reproduction, 309 W. Clark St., Champaign, IL 61820) V.1- 1969- Volume(issue)/page/year: 18,365,1978

安全

• 个人防护装备: Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
• 危险品运输编码: NONH for all modes of transport
• RTECS号: BV8153000

合成路线

566-48-3 75-36-5 ~97% 61630-32-8

文献：Andrade; Paixao; De Almeida; Fernandes Roleira; Tavares Da Silva Acta Crystallographica Section C: Crystal Structure Communications, 2007 , vol. 63, # 6 p. o330-o331

108-24-7 566-48-3 ~66% 61630-32-8

文献：Marsh, David A.; Brodie, Harry J.; Garrett, Wesley; Tsai-Morris, Chon-Hwa; Brodie, Angela M. H. Journal of Medicinal Chemistry, 1985 , vol. 28, # 6 p. 788 - 795

77057-73-9 ~% 61630-32-8

文献：Mann, John; Pietrzak, Barbara Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 11 p. 2681 - 2685

566-48-3 5538-51-2 ~% 1373116-44-9 61630-32-8

文献：Varela, Carla; Tavares Da Silva, Elisiario J.; Amaral, Cristina; Correia Da Silva, Georgina; Baptista, Teresa; Alcaro, Stefano; Costa, Giosue; Carvalho, Rui A.; Teixeira, Natercia A. A.; Roleira, Fernanda M. F. Journal of Medicinal Chemistry, 2012 , vol. 55, # 8 p. 3992 - 4002

108-24-7 66880-12-4 ~% 61630-32-8

文献：Mann, John; Pietrzak, Barbara Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 11 p. 2681 - 2685

上下游产品

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566-48-3 75-36-5 108-24-7 77057-73-9
5538-51-2 66880-12-4
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