2728-04-3

• 常用中文名：N,N-二乙基-2-甲基苯甲酰胺
• 常用英文名：Benzamide,N,N-diethyl-2-methyl-
• CAS号：2728-04-3
• 分子式：C₁₂H₁₇NO
• 分子量：191.26900
• 发布时间：2018-10-16 13:11:34
• 更新时间：2024-01-05 18:45:06

名称

• 中文名: N,N-二乙基-2-甲基苯甲酰胺
• 英文名: N,N-Diethyl-2-methylbenzamide
• 英文别名: o-toluic acid diethylamide; 2-Methyl-N,N-diethylbenzamide; o-DETA; o-DEET; N,N-diethyl-2-toluamide; N,N-diethyl ortho-toluamide; Benzamide,N,N-diethyl-2-methyl; N,N-diethyl-2-methyl-benzamide; N,N-Diethyl-o-toluamide

物化性质

• 密度: 0.985g/cm3
• 沸点: 316.7ºC at 760mmHg
• 分子式: C₁₂H₁₇NO
• 分子量: 191.26900
• 闪点: 139.8ºC
• 精确质量: 191.13100
• PSA: 20.31000
• LogP: 2.47700

MSDS

Material Safety Data Sheet Section1. Identification of the substance Product Name: N,N-Diethyl-2-methylbenzamide Synonyms: Section2. Hazards identification Harmful by inhalation, in contact with skin, and if swallowed. Section3. Composition/information on ingredients. Ingredient name:N,N-Diethyl-2-methylbenzamide CAS number:2728-04-3 Section4. First aid measures Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing contaminated clothing and shoes. If irritation persists, seek medical attention. Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical attention. Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention. Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention. Section5. Fire fighting measures In the event of a fire involving this material, alone or in combination with other materials, use dry powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus should be worn. Section6. Accidental release measures Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national standards. Respiratory precaution:Wear approved mask/respirator Hand precaution:Wear suitable gloves/gauntlets Skin protection:Wear suitable protective clothing Eye protection:Wear suitable eye protection Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container for disposal. See section 12. Environmental precautions: Do not allow material to enter drains or water courses. Section7. Handling and storage Handling:This product should be handled only by, or under the close supervision of, those properly qualified in the handling and use of potentially hazardous chemicals, who should take into account the fire, health and chemical hazard data given on this sheet. Store in closed vessels. Storage: Section8. Exposure Controls / Personal protection Engineering Controls: Use only in a chemical fume hood. Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles. General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse. Section9. Physical and chemical properties Appearance:Not specified Boiling point:No data No data Melting point: Flash point:No data Density:No data Molecular formula:C12H17NO Molecular weight:191.3 Section10. Stability and reactivity Conditions to avoid: Heat, flames and sparks. Materials to avoid: Oxidizing agents. Possible hazardous combustion products: Carbon monoxide, nitrogen oxides. Section11. Toxicological information No data. Section12. Ecological information No data. Section13. Disposal consideration Arrange disposal as special waste, by licensed disposal company, in consultation with local waste disposal authority, in accordance with national and regional regulations. Section14. Transportation information Non-harzardous for air and ground transportation. Section15. Regulatory information No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302, or have known CAS numbers that exceed the threshold reporting levels established by SARA Title III, Section 313. SECTION 16 - ADDITIONAL INFORMATION N/A

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : XS3850000 CHEMICAL NAME : o-Toluamide, N,N-diethyl- CAS REGISTRY NUMBER : 2728-04-3 BEILSTEIN REFERENCE NO. : 2257532 LAST UPDATED : 199707 DATA ITEMS CITED : 5 MOLECULAR FORMULA : C12-H17-N-O MOLECULAR WEIGHT : 191.30 WISWESSER LINE NOTATION : 2N2&VR B1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : Standard Draize test ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Human REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 1,97,1959 TYPE OF TEST : Standard Draize test ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 1,97,1959 ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1210 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 7,772,1965 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 52500 mg/kg/30W-C TOXIC EFFECTS : Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight Nutritional and Gross Metabolic - weight loss or decreased weight gain REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 7,772,1965 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X1410 No. of Facilities: 180 (estimated) No. of Industries: 2 No. of Occupations: 4 No. of Employees: 4511 (estimated)

安全

• 海关编码: 2924299090

合成路线

615-37-2 201230-82-2 109-89-7 ~92% 2728-04-3

文献：Mei, Hui; Hu, Jianglin; Xiao, Se; Lei, Yizhu; Li, Guangxing Applied Catalysis A: General, 2014 , vol. 475, p. 40 - 47

933-88-0 109-89-7 ~98% 2728-04-3

文献：Enders, Dieter; Braig, Volker; Boudou, Marine; Raabe, Gerhard Synthesis, 2004 , # 18 p. 2980 - 2990

2523-98-0 529-20-4 ~81% 2728-04-3

文献：Pathak, Uma; Bhattacharyya, Shubhankar; Pandey, Lokesh Kumar; Mathur, Sweta; Jain, Rajeev RSC Advances, 2014 , vol. 4, # 8 p. 3900 - 3903

1696-17-9 74-88-4 ~87% 2728-04-3

文献：Seganish, W. Michael; DeShong, Philip Journal of Organic Chemistry, 2004 , vol. 69, # 20 p. 6790 - 6795

118-90-1 ~% 2728-04-3

文献：Khadka, Daulat Bikram; Yang, Su Hui; Cho, Suk Hee; Zhao, Chao; Cho, Won-Jea Tetrahedron, 2012 , vol. 68, # 1 p. 250 - 261

95-49-8 109-89-7 ~% 2728-04-3

文献：McCabe et al. Journal of Organic Chemistry, 1954 , vol. 19, p. 493,496

1696-17-9 7393-13-7 74-88-4 ~23% 2728-04-3 详细

文献：Watanabe; Date; Kawanishi; Hori; Furukawa Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 10 p. 2637 - 2643

1696-17-9 74-88-4 ~% 2728-04-3 57806-77-6 详细

文献：Eaton, Philip E.; Martin, Ronald M. Journal of Organic Chemistry, 1988 , vol. 53, # 12 p. 2728 - 2732

上下游产品

上游产品  10
615-37-2 201230-82-2 109-89-7 933-88-0
2523-98-0 529-20-4 1696-17-9 74-88-4
118-90-1 95-49-8
下游产品  10
143882-36-4 529-34-0 89-71-4 148180-61-4
103258-38-4 26278-74-0 2674-44-4 29910-92-7
29539-21-7 73318-30-6

海关

海关编码	2924299090
中文概述	2924299090. 其他环酰胺（包括环氨基甲酸酯）（包括其衍生物以及他们的盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 包装
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%