21492-45-5

• 常用中文名：1-(4-fluorophenyl)-4-[3-(2-methoxyphenoxy)pyrrolidin-1-yl]butan-1-one,hydrochloride
• 常用英文名：1-(4-fluorophenyl)-4-[3-(2-methoxyphenoxy)pyrrolidin-1-yl]butan-1-one,hydrochloride
• CAS号：21492-45-5
• 分子式：C₂₁H₂₅ClFNO₃
• 分子量：393.88000
• 发布时间：2016-10-28 10:00:56
• 更新时间：2024-04-03 12:30:07

名称

• 英文名: 1-(4-fluorophenyl)-4-[3-(2-methoxyphenoxy)pyrrolidin-1-yl]butan-1-one,hydrochloride
• 英文别名: ahr-1900

物化性质

• 沸点: 492.1ºC at 760 mmHg
• 分子式: C₂₁H₂₅ClFNO₃
• 分子量: 393.88000
• 闪点: 251.4ºC
• 精确质量: 393.15100
• PSA: 38.77000
• LogP: 4.69040
• 蒸汽压: 7.94E-10mmHg at 25°C

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : EU3600000 CHEMICAL NAME : Butyrophenone, 4'-fluoro-4-(3-(2-methoxyphenoxy)-1-pyrrolidinyl)-, hydrochloride CAS REGISTRY NUMBER : 21492-45-5 LAST UPDATED : 199012 DATA ITEMS CITED : 5 MOLECULAR FORMULA : C21-H24-F-N-O3.Cl-H MOLECULAR WEIGHT : 393.92 WISWESSER LINE NOTATION : T5NTJ A3VR DF& COR BO1 &GH HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 241 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,183,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 84 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,183,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 40 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,183,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 179 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,183,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 353 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,183,1972