54122-57-5

• 常用中文名：2-(1-methoxy-2-methylpropylidene)propanedinitrile
• 常用英文名：2-(1-methoxy-2-methylpropylidene)propanedinitrile
• CAS号：54122-57-5
• 分子式：C₈H₁₀N₂O
• 分子量：150.17800
• 发布时间：2017-12-10 15:52:01
• 更新时间：2025-09-29 23:28:10

名称

• 英文名: 2-(1-methoxy-2-methylpropylidene)propanedinitrile
• 英文别名: isopropylmethoxymethylene malononitrile; 2-(1-methoxy-2-methyl-propylidene)-malononitrile; 2-(1-methoxy-2-methylpropylidene)malononitnle; (1-methoxy-2-methylpropylidene)propanedinitrile; Propanedinitrile,(1-methoxy-2-methylpropylidene)

物化性质

• 分子式: C₈H₁₀N₂O
• 分子量: 150.17800
• 精确质量: 150.07900
• PSA: 56.81000
• LogP: 1.59006

合成路线

40798-08-1 77-78-1 ~63% 54122-57-5

文献：SMITHKLINE BEECHAM CORPORATION Patent: WO2004/9602 A1, 2004 ; Location in patent: Page 83-84 ; WO 2004/009602 A1

40798-08-1 ~32% 54122-57-5

文献：SUMITOMO PHARMACEUTICALS COMPANY, LIMITED Patent: EP885890 A1, 1998 ; EP 0885890 A1

77-78-1 476371-59-2 ~30% 54122-57-5

文献：Kraybill, Brian C.; Elkin, Lisa L.; Blethrow, Justin D.; Morgan, David O.; Shokat, Kevan M. Journal of the American Chemical Society, 2002 , vol. 124, # 41 p. 12118 - 12128

186581-53-3 40798-08-1 ~% 54122-57-5

文献：XENOVA LIMITED Patent: WO2004/65389 A1, 2004 ; Location in patent: Page 32-33 ; WO 2004/065389 A1

40798-08-1 18107-18-1 ~% 54122-57-5

文献：Bussenius, Joerg; Anand, Neel K.; Blazey, Charles M.; Bowles, Owen J.; Bannen, Lynne Canne; Chan, Diva S.-M.; Chen, Baili; Co, Erick W.; Costanzo, Simona; Defina, Steven C.; Dubenko, Larisa; Engst, Stefan; Franzini, Maurizio; Huang, Ping; Jammalamadaka, Vasu; Khoury, Richard G.; Kim, Moon H.; Klein, Rhett R.; Laird, Douglas; Le, Donna T.; Mac, Morrison B.; Matthews, David J.; Markby, David; Miller, Nicole; Nuss, John M.; Parks, Jason J.; Tsang, Tsze H.; Tsuhako, Amy L.; Wang, Yong; Xu, Wei; Rice, Kenneth D. Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 6 p. 2283 - 2286

上下游产品

上游产品  4
40798-08-1 77-78-1 186581-53-3 18107-18-1
下游产品  1
476371-64-9