763111-49-5

• 常用中文名：KU-0058948
• 常用英文名：KU-0058948
• CAS号：763111-49-5
• 分子式：C₂₁H₂₁FN₄O₂
• 分子量：380.41500
• 发布时间：2016-11-09 09:44:38
• 更新时间：2024-01-15 10:08:42

名称

• 英文名: 4-[3-(1,4-Diazepan-1-ylcarbonyl)-4-fluorobenzyl]-1(2H)-phthalazin one

物化性质

• 密度: 1.36g/cm3
• 分子式: C₂₁H₂₁FN₄O₂
• 分子量: 380.41500
• 精确质量: 380.16500
• PSA: 78.35000
• LogP: 2.76750
• 折射率: 1.667

合成路线

874116-49-1 ~64% 763111-49-5

文献：Menear, Keith A.; Adcock, Claire; Boulter, Robert; Cockcroft, Xiao-Ling; Copsey, Louise; Cranston, Aaron; Dillon, Krystyna J.; Drzewiecki, Jan; Garman, Sheila; Gomez, Sylvie; Javaid, Hashim; Kerrigan, Frank; Knights, Charlotte; Lau, Alan; Loh Jr., Vincent M.; Matthews, Ian T. W.; Moore, Stephen; O'Connor, Mark J.; Smith, Graeme C. M.; Martin, Niall M. B. Journal of Medicinal Chemistry, 2008 , vol. 51, # 20 p. 6581 - 6591

763114-26-7 ~65% 763111-49-5

文献：Kudos Pharmaceuticals Limited; Maybridge Limited Patent: US2005/59663 A1, 2005 ; US 20050059663 A1

763114-25-6 112275-50-0 ~% 763111-49-5

文献：THE JOHNS HOPKINS UNIVERSITY; KERN, Scott; GHOSH, Soma Patent: WO2014/78633 A1, 2014 ; Location in patent: Paragraph 0078 ;

112275-50-0 ~% 763111-49-5

文献：Cockcroft, Xiao-Ling; Dillon, Krystyna J.; Dixon, Lesley; Drzewiecki, Jan; Kerrigan, Frank; Loh Jr., Vincent M.; Martin, Niall M.B.; Menear, Keith A.; Smith, Graeme C.M. Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 4 p. 1040 - 1044

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874116-49-1 763114-26-7 763114-25-6 112275-50-0
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