99-79-6

• 常用中文名：碘苯酯
• 常用英文名：iofendylate
• CAS号：99-79-6
• 分子式：C₁₉H₂₉IO₂
• 分子量：416.33700
• 相关类别： 原料药 诊断用药 影象检查用药
• 发布时间：2018-09-20 08:09:45
• 更新时间：2025-08-30 19:05:28
• 碘苯酯(泛不透明)是一种高度亲脂性物质,可用作造影剂。碘苯酯主要用于脑和脊髓可视化[1][2]。

名称

• 中文名: 碘苯酯
• 英文名: Ethyl 10-(4-iodophenyl)undecanoate
• 英文别名: Iophendylate,p; 10-(4-Jod-phenyl)-undecansaeure-aethylester; Aethyl-9-(p-Iodphenyl)-9-methyl-decanoat; Ethiodan; Iofendylate; Mulsopaque; Neurotrast; IOPHENDYLATE; 10-(4-iodo-phenyl)-undecanoic acid ethyl ester; Jofendylatum; Myodil; Myodyl

物化性质

• 密度: 1.261g/cm3
• 沸点: 421.2ºC at 760mmHg
• 熔点: 25°C
• 分子式: C₁₉H₂₉IO₂
• 分子量: 416.33700
• 闪点: 208.5ºC
• 精确质量: 416.12100
• PSA: 26.30000
• LogP: 6.07860
• 折射率: 1.526

生物活性

• 描述: 碘苯酯(泛不透明)是一种高度亲脂性物质,可用作造影剂。碘苯酯主要用于脑和脊髓可视化[1][2]。
• 相关类别:
  研究领域 >> 其他
  信号通路 >> 其他 >> 其他

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : YQ2550000 CHEMICAL NAME : Undecanoic acid, 10-(p-iodophenyl)-, ethyl ester CAS REGISTRY NUMBER : 99-79-6 BEILSTEIN REFERENCE NO. : 2661373 LAST UPDATED : 199612 DATA ITEMS CITED : 6 MOLECULAR FORMULA : C19-H29-I-O2 MOLECULAR WEIGHT : 416.38 WISWESSER LINE NOTATION : IR DY1&8VO2 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 2100 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,65,1982 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1130 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 34,38,1971 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 5640 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 34,38,1971 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : RADLAX Radiology. (Radiological Soc. of North America, 20th & Northampton Sts., Easton, PA 18042) V.1- 1923- Volume(issue)/page/year: 43,230,1944 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 34,38,1971 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4722 No. of Facilities: 16 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 702 (estimated) No. of Female Employees: 359 (estimated)

安全

• 海关编码: 2916399090

合成路线

692-86-4 ~% 99-79-6

文献：Journal of the American Chemical Society, , vol. 64, p. 1436,1438

上下游产品

上游产品  1
692-86-4
下游产品  1
67987-28-4

海关

海关编码	2916399090
中文概述	2916399090 其他芳香一元羧酸. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 丙烯酸、丙烯酸盐或酯应报明包装
Summary	2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%