337-68-8

• 常用中文名：16-beta-Hydroxy-3,11-dioxopregna-4,17(20)-dien-21-oic acid, gamma-lactone
• 常用英文名：16-beta-Hydroxy-3,11-dioxopregna-4,17(20)-dien-21-oic acid, gamma-lactone
• CAS号：337-68-8
• 分子式：C₂₁H₂₄O₄
• 分子量：340.41300
• 发布时间：2017-10-03 07:47:51
• 更新时间：2024-04-02 20:33:43

名称

• 英文名: Pregna-4,17(20)-dien-21-oic acid, 16.β.-hydroxy-3,11-dioxo-, .γ.-lactone
• 英文别名: [3-[5-[5-(4,5-dihydroxy-6-methyloxan-2-yl)oxy-4-hydroxy-6-methyloxan-2-yl]oxy-4-hydroxy-6-methyloxan-2-yl]oxy-14-hydroxy-10,13-dimethyl-17-(5-oxo-2H-furan-3-yl)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-16-yl] formate; [3-[5-[5-(4,5-dihydroxy-6-methyl-oxan-2-yl)oxy-4-hydroxy-6-methyl-oxan-2-yl]oxy-4-hydroxy-6-methyl-oxan-2-yl]oxy-14-hydroxy-10,13-dimethyl-17-(5-oxo-2H-furan-3-yl)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-16-yl] methanoate; O16-Formyl-gitoxin; 16-Formylgitoxin; formic acid [3-[5-[5-(4,5-dihydroxy-6-methyl-tetrahydropyran-2-yl)oxy-4-hydroxy-6-methyl-tetrahydropyran-2-yl]oxy-4-hydroxy-6-methyl-tetrahydropyran-2-yl]oxy-14-hydroxy-17-(5-keto-2H-furan-3-yl)-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-16-yl] ester

物化性质

• 密度: 1.27g/cm3
• 沸点: 574.6ºC at 760 mmHg
• 分子式: C₂₁H₂₄O₄
• 分子量: 340.41300
• 闪点: 253.6ºC
• 精确质量: 340.16700
• PSA: 60.44000
• LogP: 3.15900
• 折射率: 1.594

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : TU4156000 CHEMICAL NAME : Pregna-4,17(20)-dien-21-oic acid, 16-beta-hydroxy-3,11-dioxo-, gamma-lactone CAS REGISTRY NUMBER : 337-68-8 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C21-H24-O4 MOLECULAR WEIGHT : 340.45 WISWESSER LINE NOTATION : T F5 E5 B666 CV HVO RV PU JH&TTTTJ A1 E1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 79 mg/kg TOXIC EFFECTS : Tumorigenic - active as anti-cancer agent REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 7,348,1964