CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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RP6159000
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CHEMICAL NAME :
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2H-1,3,2-Oxazaphosphorine, tetrahydro-2-(bis(2-chloroethyl)amino)-6-trifluoromet hyl-, 2-oxide
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CAS REGISTRY NUMBER :
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57165-71-6
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LAST UPDATED :
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199612
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DATA ITEMS CITED :
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2
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MOLECULAR FORMULA :
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C8-H14-Cl2-F3-N2-O2-P
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MOLECULAR WEIGHT :
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329.11
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WISWESSER LINE NOTATION :
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T6MPOTJ BO BN2G2G DXFFF
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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224 mg/kg
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TOXIC EFFECTS :
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Tumorigenic - active as anti-cancer agent
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REFERENCE :
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JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 18,1106,1975
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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400 mg/kg
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TOXIC EFFECTS :
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Tumorigenic - active as anti-cancer agent
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REFERENCE :
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JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 18,1106,1975
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