827026-45-9

• 常用中文名：3-(4-硝基-1-氧代-1,3-二氢异吲哚-2-基)哌啶-2,6-二酮
• 常用英文名：3-(4-Nitro-1-oxo-1,3-dihydroisoindol-2-yl)piperidine-2,6-dione
• CAS号：827026-45-9
• 分子式：C₁₃H₁₁N₃O₅
• 分子量：289.243
• 发布时间：2018-08-23 11:30:17
• 更新时间：2024-01-08 00:04:01

名称

• 中文名: 3-(4-硝基-1-氧代-1,3-二氢异吲哚-2-基)哌啶-2,6-二酮
• 英文名: (3S)-3-(4-Nitro-1-oxo-1,3-dihydro-2H-isoindol-2-yl)piperidine-2,6-dione
• 中文别名: 来那度胺中间体; 来那度胺中间体1 3-(4-硝基-1-氧代异吲哚-2-基)哌啶-2,6-二酮; 来那度胺中间体1; 3-(4-硝基-1-氧代异吲哚-2-基)哌啶-2,6-二酮; 3-(4-硝基-L,3一二氢-1一氧代.2H-异吲哚-2-基)-2,6-哌啶二酮
• 英文别名: 3-(4-Nitro-1-oxo-1,3-dihydro-2H-isoindol-2-yl)piperidin-2,6-dion; 3-(4-Nitro-1-oxo-1,3-dihydro-2H-isoindol-2-yl)-2,6-piperidinedione; 3-(7-nitro-3-oxo-1H-isoindol-2-yl)piperidine-2,6-dione; 2,6-Piperidinedione, 3-(1,3-dihydro-4-nitro-1-oxo-2H-isoindol-2-yl)-; 3-(4-Nitro-1-oxo-1,3-dihydro-2H-isoindol-2-yl)piperidine-2,6-dione; 3-(4-Nitro-1-oxo-1,3-dihydroisoindol-2-yl)piperidine-2,6-dione

物化性质

• 密度: 1.5±0.1 g/cm3
• 沸点: 616.6±55.0 °C at 760 mmHg
• 分子式: C₁₃H₁₁N₃O₅
• 分子量: 289.243
• 闪点: 326.7±31.5 °C
• 精确质量: 289.069885
• PSA: 112.30000
• LogP: -0.38
• 蒸汽压: 0.0±1.8 mmHg at 25°C
• 折射率: 1.657
• 储存条件: 2-8°C

安全

• 海关编码: 2925190090

合成路线

98475-07-1 2353-44-8 ~77% 827026-45-9

文献：CELGENE CORPORATION; LI, Ying; XU, Jean; KLOPFER, Kevin, J. Patent: WO2013/126394 A1, 2013 ; Location in patent: Paragraph 00123-00125 ;

1198299-72-7 ~80% 827026-45-9

文献：NANJING CAVENDISH BIO-ENGINEERING TECHNOLOGY CO., LTD.; YAN, Rong; YANG, Hao; XU, Yongxiang Patent: WO2010/139266 A1, 2010 ; Location in patent: Page/Page column 55 ;

24666-56-6 98475-07-1 ~94% 827026-45-9

文献：RANBAXY LABORATORIES LIMITED; KAPOOR, Munish; KUMAR, Saridi, Madhava, Dileep; MURUGESAN, Balaguru; SATHYANARAYANA, Swargam; THAPER, Rajesh, Kumar; PRASAD, Mohan Patent: WO2011/27326 A1, 2011 ; Location in patent: Page/Page column 11 ;

98475-07-1 24666-55-5 ~% 827026-45-9

文献：HETERO RESEARCH FOUNDATION; PARTHASARADHI REDDY, Bandi; RATHNAKAR REDDY, Kura; MURALIDHARA REDDY, Dasari; RAMAKRISHNA REDDY, Matta; VAMSI KRISHNA, Bandi Patent: WO2013/5229 A1, 2013 ; Location in patent: Page/Page column 8 ;

59382-59-1 ~% 827026-45-9

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 9, # 11 p. 1625 - 1630

2650-64-8 ~% 827026-45-9

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 9, # 11 p. 1625 - 1630

24666-55-5 ~% 827026-45-9

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 9, # 11 p. 1625 - 1630

6398-06-7 ~% 827026-45-9

文献：WO2011/50962 A1, ;

827026-43-7 ~% 827026-45-9

文献：WO2005/5409 A1, ; Page/Page column 7 ;

上下游产品

上游产品  9
98475-07-1 2353-44-8 1198299-72-7 24666-56-6
24666-55-5 59382-59-1 2650-64-8 6398-06-7
827026-43-7
下游产品  0

海关

海关编码	2925190090
中文概述	2925190090 其他酰亚胺及其衍生物盐. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%