130753-13-8

• 常用中文名：3-氧代-8-氮杂双环[3,2,1]辛烷-8-羧酸苄酯
• 常用英文名：Benzyl 3-oxo-8-azabicyclo[3.2.1]octane-8-carboxylate
• CAS号：130753-13-8
• 分子式：C₁₅H₁₇NO₃
• 分子量：259.300
• 相关类别： 化学试剂 有机试剂 芳烃
• 发布时间：2018-04-27 08:00:00
• 更新时间：2024-01-04 18:09:37

名称

• 中文名: N-Cbz-去甲托品酮
• 英文名: N-Cbz-Nortropinone
• 中文别名: 3-氧代-8-氮杂双环[3,2,1]辛-8-羧酸苄酯; N-苄氧羰基去甲托品酮
• 英文别名: 8-Azabicyclo[3.2.1]octane-8-carboxylic acid, 3-oxo-, phenylmethyl ester, (1R,5S)-; benzyl 4-oxotropane-N-carboxylate; 8-Cbz-3-oxo-8-azabicyclo[3.2.1]octane; N-Cbz-Notropinone; 8-benzyloxycarbonyl-8-azabicyclo[3.2.1]octan-3-one; N-Cbz nortropinone; Benzyl (1R,5S)-3-oxo-8-azabicyclo[3.2.1]octane-8-carboxylate; 3-oxo-8-azabicyclo[3.2.1]octan-8-carboxylic acid benzyl ester; cbz-protected 8-aza-bicyclo[3.2.1]octan-3-one; 8-Azabicyclo[3.2.1]octane-8-carboxylic acid, 3-oxo-, phenylmethyl ester; Benzyl 3-oxo-8-azabicyclo[3.2.1]octane-8-carboxylate; N-Cbz-4-Nortropinone

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 415.7±45.0 °C at 760 mmHg
• 分子式: C₁₅H₁₇NO₃
• 分子量: 259.300
• 闪点: 205.2±28.7 °C
• 精确质量: 259.120850
• PSA: 46.61000
• LogP: 1.41
• 蒸汽压: 0.0±1.0 mmHg at 25°C
• 折射率: 1.580
• 储存条件: 室温

安全

• 海关编码: 2933990090

合成路线

25602-68-0 501-53-1 ~86% 130753-13-8

文献：VERTEX PHARMACEUTICALS, INCORPORATED Patent: WO2006/23852 A2, 2006 ; Location in patent: Page/Page column 84 ; WO 2006/023852 A2

532-24-1 501-53-1 ~55% 130753-13-8

文献：LUPIN LIMITED; ROY, Bhairab, Nath; KAMBOJ, Rajender, Kumar; GEORGE, Shaji, K.; VENUGOPAL, Spinvin, C.; SHANMUGVADIVELU, Muthu, Kumaran; SINHA, Neelima Patent: WO2011/18796 A1, 2011 ; Location in patent: Page/Page column 19 ; WO 2011/018796 A1

5632-84-8 501-53-1 ~% 130753-13-8

文献：WO2007/100670 A1, ; Page/Page column 47 ; WO 2007/100670 A1

96951-89-2 ~99% 130753-13-8

文献：Fei, Zhongbo; Wu, Quanbing; Zhang, Fei; Cao, Yudong; Liu, Chuanqin; Shieh, Wen-Chung; Xue, Song; McKenna, Joe; Prasad, Kapa; Prashad, Mahavir; Baeschlin, Daniel; Namoto, Kenji Journal of Organic Chemistry, 2008 , vol. 73, # 22 p. 9016 - 9021

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%