间硝基苯胺

间硝基苯胺用途

用途一：用于有机合成及松木颜色的检验，也用作染料中间体
用途二：用作医药及染料中间体
用途三：主要用作有机合成中间体和染料中间体。可用作冰染染料橙色基R和制取色酚AS-BS。将间硝基苯胺与环氧乙烷进行羟乙基化，可制得3-硝基-N，N-二乙醇基苯胺。
用途四：用作染料中间体及及用于有机合成，也用于松木颜色的检验,酸碱指示剂，pH6.8(无色)-8.6(黄)。
用途五：用作染料中间体及及用于有机合成，也用于松木颜色的检验,酸碱指示剂，pH6.8(无色)-8.6(黄)。用于ICP-AES、AAS、AFS、ICP-MS、离子色谱等。滴定分析用标准溶液。

间硝基苯胺名称

[ CAS 号 ]:
99-09-2

[ 中文名 ]:
3-硝基苯胺

[ 英文名 ]:
3-Nitroaniline

[中文别名 ]:

间硝基苯胺

[英文别名 ]:

3-amino-nitrobenzene
Nitroaniline
3-nitrophenylamine
Nitranilin
aniline, 3-nitro-
Benzenamine, 3-nitro-
3-Nitrobenzenamine
3-Aminonitrobenzene
Azobase MNA
Fast Orange Base R

间硝基苯胺物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
307.0±15.0 °C at 760 mmHg

[ 熔点 ]:
111-114 °C(lit.)

[ 分子式 ]:
C₆H₆N₂O₂

[ 分子量 ]:
138.124

[ 闪点 ]:
139.5±20.4 °C

[ 精确质量 ]:
138.042923

[ PSA ]:
71.84000

[ LogP ]:
1.37

[ 外观性状 ]:
黄色粉末

[ 蒸汽压 ]:
0.0±0.7 mmHg at 25°C

[ 折射率 ]:
1.634

[ 储存条件 ]:
库房通风低温干燥,与氧化剂、酸类、食品添加剂分开存放

[ 水溶解性 ]:
1.25 g/L

间硝基苯胺MSDS

详细MSDS(安全技术说明书)

间硝基苯胺毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BY6825000

CHEMICAL NAME :: Aniline, m-nitro-

CAS REGISTRY NUMBER :: 99-09-2

LAST UPDATED :: 199710

DATA ITEMS CITED :: 14

MOLECULAR FORMULA :: C6-H6-N2-O2

MOLECULAR WEIGHT :: 138.14

WISWESSER LINE NOTATION :: ZR CNW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 535 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 308 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 70 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea Lungs, Thorax, or Respiration - other changes

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 450 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - quail

DOSE/DURATION :: 562 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 420 mg/kg/28D-I

TOXIC EFFECTS :: Liver - changes in liver weight Endocrine - changes in spleen weight Blood - normocytic anemia

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2940 mg/kg/3W-I

TOXIC EFFECTS :: Blood - other changes Blood - changes in erythrocyte (RBC) count

MUTATION DATA

TYPE OF TEST :: DNA repair

TEST SYSTEM :: Bacteria - Bacillus subtilis

DOSE/DURATION :: 5 mg/disc

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 170,11,1986

间硝基苯胺安全信息

[ 符号 ]:

GHS06, GHS08

[ 信号词 ]:
Danger

[ 危害声明 ]:
H301-H311-H331-H373-H412

[ 警示性声明 ]:
P261-P273-P280-P301 + P310-P311

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
T:Toxic;

[ 风险声明 (欧洲) ]:
R23/24/25;R33;R52/53

[ 安全声明 (欧洲) ]:
S28-S36/37-S45-S61-S28A

[ 危险品运输编码 ]:
UN 1661 6.1/PG 2

[ WGK德国 ]:
2

[ RTECS号 ]:
BY6825000

[ 包装等级 ]:
II

[ 危险类别 ]:
6.1

[ 海关编码 ]:
29214210

间硝基苯胺合成路线

详细合成路线

间硝基苯胺上下游产品

间硝基苯胺上游产品

间硝基苯胺下游产品

间硝基苯胺制备

以硝基苯为原料，以硝酸和硫酸配成混酸进行硝化生成间二硝基苯，经亚硫酸精制，得间二硝基苯成品。用硫磺和硫化钠为原料，制取多硫化钠，用多硫化钠将间二硝基苯还原成间硝基苯胺，反应产物经重结晶、过滤得成品。原料消耗定额：硝基苯1319kg/t、硝酸845kg/t、硫酸2050kg/t、硫化钠707kg/t、硫磺271kg/t。

间硝基苯胺海关

[ 海关编码 ]: 2921420090

[ 中文概述 ]:
2921420090 其他苯胺衍生物及其盐. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
HS:2921420090 aniline derivatives and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

间硝基苯胺文献

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