N,N-二异丙基-2-苯并噻唑次磺酰胺

N,N-二异丙基-2-苯并噻唑次磺酰胺用途

本品为后效性促进剂。在天然橡胶中延迟作用比促进剂NOBS(N氧二亚乙基-2-苯并噻唑次磺酰胺)大，而且在硫化温度下硫化速度也较快。硫化平坦性宽，一般可采用较高的硫化温度（130～160℃）。通常用于制造轮胎、胶管、胶带、工业制品等。一般用量为0.4～1.5份，并配以2.5～0.5份的硫黄。

N,N-二异丙基-2-苯并噻唑次磺酰胺名称

[ CAS 号 ]:
95-29-4

[ 中文名 ]:
N,N-二异丙基-2-苯并噻唑次磺酰胺

[ 英文名 ]:
N,N-diisopropylbenzothiazole-2-sulphenamide

[中文别名 ]:

[英文别名 ]:

N,N-di-isopropyl-benzothiazolesulphenamide
N,N-diisopropylbenzothiazole-2-sulphenamide
N,N-Diisopropyl-2-benzothiazolesulfenamide
benzothiazole-2-sulfenic acid diisopropylamide
DIPAC
Benzothiazol-2-sulfensaeure-diisopropylamid
N,N-diisopropylbenzothiazole-2-sulfenamide
EINECS 202-407-0
DIPAK
DIBS

N,N-二异丙基-2-苯并噻唑次磺酰胺物理化学性质

[ 分子式 ]:
C₁₃H₁₈N₂S₂

[ 分子量 ]:
266.42500

[ 精确质量 ]:
266.09100

[ PSA ]:
69.67000

[ LogP ]:
4.42220

N,N-二异丙基-2-苯并噻唑次磺酰胺毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DL6330000

CHEMICAL NAME :: 2-Benzothiazolesulfenamide, N,N-diisopropyl-

CAS REGISTRY NUMBER :: 95-29-4

BEILSTEIN REFERENCE NO. :: 0177776

LAST UPDATED :: 199712

DATA ITEMS CITED :: 10

MOLECULAR FORMULA :: C13-H18-N2-S2

MOLECULAR WEIGHT :: 266.45

WISWESSER LINE NOTATION :: T56 BN DSJ CSO&NY1&1&Y1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0538647

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0538647 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5200 mg/kg

TOXIC EFFECTS :: Behavioral - ataxia Kidney, Ureter, Bladder - other changes in urine composition Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0538647

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3892 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 8(7),39,1964

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0538647 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 1820 mg/kg/17W-I

TOXIC EFFECTS :: Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 8(7),39,1964 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7138 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 18 No. of Employees: 3940 (estimated) No. of Female Employees: 14 (estimated)

N,N-二异丙基-2-苯并噻唑次磺酰胺安全信息

[ 海关编码 ]:
2934999090

N,N-二异丙基-2-苯并噻唑次磺酰胺合成路线

详细合成路线

N,N-二异丙基-2-苯并噻唑次磺酰胺上下游产品

N,N-二异丙基-2-苯并噻唑次磺酰胺上游产品

N,N-二异丙基-2-苯并噻唑次磺酰胺下游产品

N,N-二异丙基-2-苯并噻唑次磺酰胺制备

（1）氯代二异丙胺的制备将有效氯含量大于25%的次氯酸钠，在激烈搅拌下，连续滴加到装有二异丙胺的反应釜内,将反应温度控制在25℃以下。反应结束后，静置分去氢氧化钠废液，制得氯代二异丙胺。

（2）将甲醇投入反应釜，再加入氯代二异丙胺、2-二硫代二苯并噻唑（促进剂DM）及二异丙胺，开动搅拌使物料溶解，升温至65℃进行反应。反应完成后，反应产物经冷却、甩滤、水洗、干燥即得成品。过滤母液进行蒸馏回收甲醇及二异丙胺盐酸盐。

N,N-二异丙基-2-苯并噻唑次磺酰胺海关

[ 海关编码 ]: 2934999090

[ 中文概述 ]:
2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%