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4-氨基马尿酸钠水合物

4-氨基马尿酸钠水合物用途

Aminohippurate sodium是一种涉及用于肾血浆流量测量肾脏医学测试的诊断剂。

4-氨基马尿酸钠水合物名称

[ CAS 号 ]:
94-16-6

[ 中文名 ]:
4-氨基马尿酸钠水合物

[ 英文名 ]:
Sodium [(4-aminobenzoyl)amino]acetate

[中文别名 ]:

对氨基马尿酸钠盐水合物

[英文别名 ]:

Sodium [(4-aminobenzoyl)amino]acetate
P-AMINOHIPPURIC ACID SODIUM SALT
Glycine, N-(4-aminobenzoyl)-, sodium salt (1:1)
EINECS 202-309-8
Sodium 2-amino-2-benzamidoacetate
MFCD00044689
Aminohippurate (sodium)

4-氨基马尿酸钠水合物生物活性

[ 描述 ]:

Aminohippurate sodium是一种涉及用于肾血浆流量测量肾脏医学测试的诊断剂。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 其他

[参考文献]

[1]. Naidoo V, et al. Diclofenac toxicity in Gyps vulture is associated with decreased uric acid excretion and not renal portal vasoconstriction. Comp Biochem Physiol C Toxicol Pharmacol. 2009 Apr;149(3):269-74.

[相关活性小分子]

4-氨基马尿酸钠水合物物理化学性质

[ 沸点 ]:
517.2ºC at 760 mmHg

[ 熔点 ]:
123-125°C

[ 分子式 ]:
C₉H₉N₂NaO₃

[ 分子量 ]:
216.169

[ 闪点 ]:
266.6ºC

[ 精确质量 ]:
216.051086

[ PSA ]:
95.25000

[ 储存条件 ]:
2-8℃

4-氨基马尿酸钠水合物MSDS

详细MSDS(安全技术说明书)

4-氨基马尿酸钠水合物毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MR8157200

CHEMICAL NAME :: Hippuric acid, p-amino-, monosodium salt

CAS REGISTRY NUMBER :: 94-16-6

LAST UPDATED :: 199712

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C9-H9-N2-O3.Na

MOLECULAR WEIGHT :: 216.19

WISWESSER LINE NOTATION :: ZR DVM1VQ &-NA-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4075 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,828,1990

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 4930 mg/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 84,147,1945

4-氨基马尿酸钠水合物安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 安全声明 (欧洲) ]:
S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
MR8157200

[ 海关编码 ]:
2924299090

4-氨基马尿酸钠水合物海关

[ 海关编码 ]: 2924299090

[ 中文概述 ]:
2924299090. 其他环酰胺（包括环氨基甲酸酯）（包括其衍生物以及他们的盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 包装

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

4-氨基马尿酸钠水合物文献

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Biochem. Pharmacol. 81 , 942-949, (2011)

Flavonoids are conjugated by phase II enzymes in humans to form glucuronidated and sulfated metabolites that are excreted in urine via the kidney. In this study, we examined the interaction between me...

Molecular evidence for an involvement of organic anion transporters (OATs) in aristolochic acid nephropathy.

Toxicology 264 , 74-79, (2009)

Aristolochic acid (AA), present in Aristolochia species, is the major causative agent in the development of severe renal failure and urothelial cancers in patients with AA nephropathy. It may also be ...

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