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1-甲基-5-硝基-2-羟甲基咪唑

1-甲基-5-硝基-2-羟甲基咪唑用途

HMMNI (Hydroxy dimetridazole) 是二甲硝唑的羟基代谢产物。Dimetridazol 是一种硝基咪唑类药物,用于对抗原生动物感染。

1-甲基-5-硝基-2-羟甲基咪唑名称

[ CAS 号 ]:
936-05-0

[ 中文名 ]:
1-甲基-5-硝基-2-羟甲基咪唑

[ 英文名 ]:
HMMNI

[中文别名 ]:

[英文别名 ]:

1-Methyl-2-hydroxymethyl-5-nitroimidazole
imidazole-2-methanol, 1-methyl-5-nitro-
1-Methyl-5-nitro-1H-imidazole-2-methanol
2-hydroxymethyl-1-methyl-5-nitroimidazole
1H-Imidazole-2-methanol, 1-methyl-5-nitro-
(1-Methyl-5-nitro-1H-imidazol-2-yl)methanol

1-甲基-5-硝基-2-羟甲基咪唑生物活性

[ 描述 ]:

HMMNI (Hydroxy dimetridazole) 是二甲硝唑的羟基代谢产物。Dimetridazol 是一种硝基咪唑类药物,用于对抗原生动物感染。

[ 相关类别 ]:

研究领域 >> 其他

[参考文献]

[1]. Cronly M, et al. Rapid confirmatory method for the determination of 11 nitroimidazoles in egg using liquid chromatography tandem mass spectrometry. J Chromatogr A. 2009;1216(46):8101‐8109.

1-甲基-5-硝基-2-羟甲基咪唑物理化学性质

[ 密度 ]:
1.5±0.1 g/cm3

[ 沸点 ]:
388.0±22.0 °C at 760 mmHg

[ 熔点 ]:
110-112ºC

[ 分子式 ]:
C₅H₇N₃O₃

[ 分子量 ]:
157.127

[ 闪点 ]:
188.5±22.3 °C

[ 精确质量 ]:
157.048737

[ PSA ]:
83.87000

[ LogP ]:
-0.49

[ 外观性状 ]:
固体;Light yellow to Yellow to Orange powder to crystal

[ 蒸汽压 ]:
0.0±0.9 mmHg at 25°C

[ 折射率 ]:
1.634

[ 储存条件 ]:
-20?C Freezer

1-甲基-5-硝基-2-羟甲基咪唑MSDS

1-甲基-5-硝基-2-羟甲基咪唑毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NI6801000

CHEMICAL NAME :: Imidazole-2-methanol, 1-methyl-5-nitro-

CAS REGISTRY NUMBER :: 936-05-0

BEILSTEIN REFERENCE NO. :: 0744944

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C5-H7-N3-O3

MOLECULAR WEIGHT :: 157.15

WISWESSER LINE NOTATION :: T5N CNJ A1 B1Q ENW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Klebsiella pneumoniae

DOSE/DURATION :: 10 umol/L/20H

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 66,207,1979

1-甲基-5-硝基-2-羟甲基咪唑安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ RTECS号 ]:
NI6801000

[ 海关编码 ]:
2933290090

1-甲基-5-硝基-2-羟甲基咪唑合成路线

1-甲基-5-硝基-2-羟甲基咪唑上下游产品

1-甲基-5-硝基-2-羟甲基咪唑上游产品

1-甲基-5-硝基-2-羟甲基咪唑下游产品

1-甲基-5-硝基-2-羟甲基咪唑海关

[ 海关编码 ]: 2933290090

[ 中文概述 ]:
2933290090. 其他结构含非稠合咪唑环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

1-甲基-5-硝基-2-羟甲基咪唑文献

Simultaneous determination of nitroimidazole residues in honey samples by high-performance liquid chromatography with ultraviolet detection.

J. AOAC Int. 90(3) , 872-8, (2007)

A rapid and sensitive high-performance liquid chromatography (LC) method was developed for the simultaneous determination of metronidazole (MNZ), dimetridazole (DMZ), ronidazole (RNZ), tinidazole (TNZ...

Confirmation of four nitroimidazoles in porcine liver by liquid chromatography-tandem mass spectrometry.

Anal. Chim. Acta 586(1-2) , 394-8, (2007)

A sensitive and reliable multiresidue method is described for analysis of ronidazole, metronidazole, dimetridazole and the common metabolite of ronidazole and dimetridazole, 2-hydroxymethyl-1-methyl-5...

Pharmacokinetics and anti-trichomonal efficacy of a dimetridazole tablet and water-soluble powder in homing pigeons (Columba livia).

J. Vet. Pharmacol. Ther. 19(1) , 62-7, (1996)

The anti-trichomonal efficacy and pharmacokinetics of dimetridazole were investigated in the homing pigeon (Columba livia). Dimetridazole was formulated for drinking water medication and as a prolonge...

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