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糖原

糖原用途

Glycogen 是糖酵解的中间产物和高能磷酸盐,它是人类、动物、真菌和细菌的能量储存形式。

糖原名称

[ CAS 号 ]:
9005-79-2

[ 中文名 ]:
α-1,6 葡聚糖

[ 英文名 ]:
Glycogen

[中文别名 ]:

[英文别名 ]:

Lyoglycogen
GLYCOGEN
Animal starch
Phytoglycogen
EINECS 232-683-8
Liver starch
MFCD00081547

糖原生物活性

[ 描述 ]:

Glycogen 是糖酵解的中间产物和高能磷酸盐,它是人类、动物、真菌和细菌的能量储存形式。

[ 相关类别 ]:

天然产物 >> 其他

研究领域 >> 代谢疾病

[ 靶点 ]

Human Endogenous Metabolite

[参考文献]

[1]. Harris RC, et al. Glycogen, glycolytic intermediates and high-energy phosphates determined in biopsy samples of musculus quadriceps femoris of man at rest. Methods and variance of values. Scand J Clin Lab Invest. 1974 Apr;33(2):109-20.

[相关活性小分子]

糖原物理化学性质

[ 密度 ]:
1.83g/cm3

[ 沸点 ]:
1027.2ºC at 760mmHg

[ 熔点 ]:
270-280 °C (dec.)

[ 分子式 ]:
C₂₄H₄₂O₂₁

[ 分子量 ]:
666.57800

[ 闪点 ]:
575ºC

[ 精确质量 ]:
666.22200

[ PSA ]:
347.83000

[ 折射率 ]:
1.687

[ 储存条件 ]:
2-8°C

[ 水溶解性 ]:
H2O: 20 mg/mL, clear to hazy, faintly yellow

糖原MSDS

详细MSDS(安全技术说明书)

糖原毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MC2700000

CHEMICAL NAME :: Glycogen

CAS REGISTRY NUMBER :: 9005-79-2

LAST UPDATED :: 199801

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intrauterine

DOSE :: 20 mg/kg

SEX/DURATION :: female 2 day(s) after conception

TOXIC EFFECTS :: Reproductive - Maternal Effects - uterus, cervix, vagina Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)

REFERENCE :: SCYYDZ Shengzhi Yu Biyun. Reproduction and Contraception. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) 1980- Volume(issue)/page/year: 11(4),7,1991 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3656 No. of Facilities: 16 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 362 (estimated) No. of Female Employees: 306 (estimated)

糖原安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
36/37/38

[ 安全声明 (欧洲) ]:
S24/25-S26

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
MC2700000

糖原制备

存在于肝和肌肉中，也存在于昆虫及低等植物中。可由肝脏用30％氢氧化钠处理，再加乙醇沉淀而制得。

糖原文献

Spermidine feeding decreases age-related locomotor activity loss and induces changes in lipid composition.

PLoS ONE 9(7) , e102435, (2014)

Spermidine is a natural polyamine involved in many important cellular functions, whose supplementation in food or water increases life span and stress resistance in several model organisms. In this wo...

Non-muscle involvement in late-onset glycogenosis II.

Acta Myol. 32(2) , 91-4, (2013)

Glycogenosis II (GSD II) is an autosomal recessive lysosomal storage disorder resulting from acid alpha-glucosidase deficiency, subsequent accumulation of glycogen in tissues, impairment of autophagic...

Clinical features of Pompe disease.

Acta Myol. 32(2) , 82-4, (2013)

Glycogen storage disease type II - also called Pompe disease or acid maltase deficiency - is an autosomal recessive metabolic disorder, caused by an accumulation of glycogen in the lysosome due to def...

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糖原