2,6-二甲基-1,3-二恶烷-4-醇乙酸酯

2,6-二甲基-1,3-二恶烷-4-醇乙酸酯名称

[ CAS 号 ]:
828-00-2

[ 中文名 ]:
2,6-二甲基-1,3-二恶烷-4-醇乙酸酯

[ 英文名 ]:
2,6-dimethyl-1,3-dioxan-4-yl acetate

[中文别名 ]:

2,6-二甲基-1,3-二氧烷-4-醇乙酸酯

[英文别名 ]:

2,6-Dimethyl-1,3-dioxan-4-yl acetate
Acetomethoxane
EINECS 212-579-9
1,3-Dioxan-4-ol,2,6-dimethyl-,acetate
Dimethoxane,commercial grade
Caswell No. 363
GIV Gard DXN-CO
GIV Gard DXN
MFCD00069040
G1V Gard DXN

2,6-二甲基-1,3-二恶烷-4-醇乙酸酯物理化学性质

[ 密度 ]:
1.067 g/mL at 25ºC(lit.)

[ 沸点 ]:
66-68ºC/3 mmHg(lit.)

[ 分子式 ]:
C₈H₁₄O₄

[ 分子量 ]:
174.19400

[ 闪点 ]:
52ºC

[ 精确质量 ]:
174.08900

[ PSA ]:
44.76000

[ LogP ]:
1.04700

[ 折射率 ]:
n20/D 1.433(lit.)

[ 储存条件 ]:
库房通风低温干燥

2,6-二甲基-1,3-二恶烷-4-醇乙酸酯MSDS

2,6-二甲基-1,3-二恶烷-4-醇乙酸酯毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AH1350000

CHEMICAL NAME :: Acetic acid, ester with 2,6-dimethyl-m-dioxan-4-ol

CAS REGISTRY NUMBER :: 828-00-2

BEILSTEIN REFERENCE NO. :: 0128710

LAST UPDATED :: 199710

DATA ITEMS CITED :: 22

MOLECULAR FORMULA :: C8-H14-O4

MOLECULAR WEIGHT :: 174.22

WISWESSER LINE NOTATION :: T6O COTJ B1 DOV1 F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1930 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2800 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 12 gm/kg/16D-I

TOXIC EFFECTS :: Gastrointestinal - other changes Liver - changes in liver weight

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 32500 mg/kg/13W-I

TOXIC EFFECTS :: Brain and Coverings - changes in brain weight Gastrointestinal - other changes Kidney, Ureter, Bladder - changes in bladder weight

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 24 gm/kg/16D-I

TOXIC EFFECTS :: Gastrointestinal - other changes Liver - changes in liver weight Related to Chronic Data - death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 948 gm/kg/88W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors Blood - leukemia

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 25750 mg/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors

TYPE OF TEST :: Sex chromosome loss and nondisjunction

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Rodent - hamster Ovary

DOSE/DURATION :: 3660 ug/L

REFERENCE :: NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-354,1989 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,177,1977 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,177,1977 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83665 No. of Facilities: 76 (estimated) No. of Industries: 2 No. of Occupations: 8 No. of Employees: 491 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83665 No. of Facilities: 11278 (estimated) No. of Industries: 114 No. of Occupations: 90 No. of Employees: 183978 (estimated) No. of Female Employees: 80381 (estimated)

2,6-二甲基-1,3-二恶烷-4-醇乙酸酯安全信息

[ 符号 ]:

GHS02, GHS07, GHS08

[ 信号词 ]:
Warning

[ 危害声明 ]:
H226-H302-H315-H319-H335-H351

[ 警示性声明 ]:
P261-P281-P305 + P351 + P338

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xn

[ 风险声明 (欧洲) ]:
36/37/38-40

[ 安全声明 (欧洲) ]:
S22;S26;S36

[ 危险品运输编码 ]:
UN 1993

[ RTECS号 ]:
AH1350000

[ 包装等级 ]:
III

[ 危险类别 ]:
3.2

2,6-二甲基-1,3-二恶烷-4-醇乙酸酯合成路线

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