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胰酶

胰酶用途

Pancreatin 是含有主要胰腺消化酶的猪胰腺提取物 (PPE)。

胰酶名称

[ CAS 号 ]:
8049-47-6

[ 中文名 ]:
胰酶

[ 英文名 ]:
Pancreatin

[中文别名 ]:

[英文别名 ]:

(9cis)-Retinoic acid
Alitretinoin
9-cis-retinoic acid
intrazyme
9Z-retinoic acid
ilozyme
pankreon
9-cis-Tretinoin
Retinoic acid, (9cis)-
beefviokase

胰酶生物活性

[ 描述 ]:

Pancreatin 是含有主要胰腺消化酶的猪胰腺提取物 (PPE)。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 内分泌

[体外研究]

胰酶是猪胰腺提取物(PPE),含有主要的胰腺消化酶。当胰酶从150增加到900 USP U/mL时,在pH 6.5下滴定的游离脂肪酸(FFA)的量分别增加了120和28％,以及脂肪分解的总程度。分别增加了79％和28％的II-LC和IIIA-LC。通过将胰酶活性从150增加到900 USPU/mL,LC-LBF的平均消化总量增加了51％,而在pH 6.5下检测到的FFA的量平均增加了55％。随着胰酶水平的增加,也观察到消化程度的增加[1]。

[参考文献]

[1]. Sassene P, et al. Toward the establishment of standardized in vitro tests for lipid-based formulations, part 6: effects of varying pancreatin and calcium levels. AAPS J. 2014 Nov;16(6):1344-57.

[相关活性小分子]

胰酶物理化学性质

[ 密度 ]:
1.0±0.1 g/cm3

[ 沸点 ]:
462.8±14.0 °C at 760 mmHg

[ 分子式 ]:
C₂₀H₂₈O₂

[ 分子量 ]:
300.435

[ 闪点 ]:
350.6±11.0 °C

[ 精确质量 ]:
300.208923

[ LogP ]:
6.83

[ 外观性状 ]:
powder | beige

[ 蒸汽压 ]:
0.0±2.5 mmHg at 25°C

[ 折射率 ]:
1.556

[ 储存条件 ]:
−20°C

[ 稳定性 ]:
Stable. Incompatible with alcohols, strong acids.

[ 水溶解性 ]:
Soluble or partly soluble in water forming a slightly turbid solution; practically insoluble in ethanol (96%) and in ether . | Soluble in water. Insoluble in alcohol and ether.

胰酶安全信息

[ 符号 ]:

GHS07, GHS08

[ 信号词 ]:
Danger

[ 危害声明 ]:
H315-H319-H334-H335

[ 警示性声明 ]:
P261-P284-P304 + P340-P305 + P351 + P338-P342 + P311

[ 危害码 (欧洲) ]:
Xn

[ 风险声明 (欧洲) ]:
36/37/38-42-42/43

[ 安全声明 (欧洲) ]:
S24;S26;S36/S37;S37/S39

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
1

[ RTECS号 ]:
RT9033000

胰酶制备

1.将动物胰脏（主要为猪的，也可用牛、羊、鸡或鸭的）搅碎，然后经过磨浆、烘干，再经乙醚浸取脱脂、粉碎后，加入适量的元明粉即为成品。

动物胰脏搅碎磨浆烘干脱脂↓乙醚

粉碎混拼↓元明粉成品

胰酶文献

ATG16L1 phosphorylation is oppositely regulated by CSNK2/casein kinase 2 and PPP1/protein phosphatase 1 which determines the fate of cardiomyocytes during hypoxia/reoxygenation.

Autophagy 11 , 1308-25, (2015)

Recent studies have shown that the phosphorylation and dephosphorylation of ULK1 and ATG13 are related to autophagy activity. Although ATG16L1 is absolutely required for autophagy induction by affecti...

In Vitro Evaluation of Cu, Fe, and Zn Bioaccessibility in the Presence of Babassu Mesocarp.

J. Agric. Food Chem. 63 , 6331-7, (2015)

In vitro gastrointestinal digestion of babassu mesocarp in the absence and presence of milk and lignin was performed to evaluate the bioaccessibility of Cu, Fe, and Zn. Extractions using NaOH solution...

Enzymes enhance degradation of the fiber-starch-protein matrix of distillers dried grains with solubles as revealed by a porcine in vitro fermentation model and microscopy.

J. Anim. Sci. 93 , 1039-51, (2015)

Effects of treating corn and wheat distillers dried grains with solubles (DDGS) with a multicarbohydrase alone or in combination with a protease on porcine in vitro fermentation characteristics and th...

更多文献

胰酶

胰酶用途

胰酶名称

胰酶生物活性

胰酶物理化学性质

胰酶安全信息

胰酶制备

胰酶文献

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