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N-(4-马来酰亚胺丁酰基)琥珀酰亚胺

N-(4-马来酰亚胺丁酰基)琥珀酰亚胺用途

GMBS 是一种双功能的交联剂。GMBS 通常用于制备抗体-酶和半抗原-载体蛋白偶联物。

N-(4-马来酰亚胺丁酰基)琥珀酰亚胺名称

[ CAS 号 ]:
80307-12-6

[ 中文名 ]:
4-马来酰亚胺基丁酸-N-琥珀酰亚胺酯

[ 英文名 ]:
gmbs

[中文别名 ]:

N-(4-马来酰亚胺丁酰基)琥珀酰亚胺

[英文别名 ]:

MFCD00036817

N-(4-马来酰亚胺丁酰基)琥珀酰亚胺生物活性

[ 描述 ]:

GMBS 是一种双功能的交联剂。GMBS 通常用于制备抗体-酶和半抗原-载体蛋白偶联物。

[ 相关类别 ]:

研究领域 >> 癌症

信号通路 >> 抗体- 药物偶联物 >> ADC连接器

[参考文献]

[1]. Ding YH, et al. Increasing the Depth of Mass-Spectrometry-Based Structural Analysis of Protein Complexes through the Use of Multiple Cross-Linkers. Anal Chem. 2016 Apr 19;88(8):4461-9.

N-(4-马来酰亚胺丁酰基)琥珀酰亚胺物理化学性质

[ 密度 ]:
1.5±0.1 g/cm3

[ 沸点 ]:
461.3±47.0 °C at 760 mmHg

[ 熔点 ]:
123-129ºC

[ 分子式 ]:
C₁₂H₁₂N₂O₆

[ 分子量 ]:
280.233

[ 闪点 ]:
232.8±29.3 °C

[ 精确质量 ]:
280.069550

[ PSA ]:
101.06000

[ LogP ]:
-1.56

[ 外观性状 ]:
白色固体

[ 蒸汽压 ]:
0.0±1.1 mmHg at 25°C

[ 折射率 ]:
1.595

[ 储存条件 ]:
2-8°C

[ 水溶解性 ]:
chloroform: 100 mg/mL

N-(4-马来酰亚胺丁酰基)琥珀酰亚胺MSDS

N-(4-马来酰亚胺丁酰基)琥珀酰亚胺安全信息

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2925190090

N-(4-马来酰亚胺丁酰基)琥珀酰亚胺合成路线

N-(4-马来酰亚胺丁酰基)琥珀酰亚胺海关

[ 海关编码 ]: 2925190090

[ 中文概述 ]:
2925190090 其他酰亚胺及其衍生物盐. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

N-(4-马来酰亚胺丁酰基)琥珀酰亚胺文献

Highly efficient capture and harvest of circulating tumor cells on a microfluidic chip integrated with herringbone and micropost arrays.

Biomed. Microdevices 17(2) , 39, (2015)

Circulating tumor cells (CTCs), which are derived from primary tumor site and transported to distant organs, are considered as the major cause of metastasis. So far, various techniques have been appli...

A chitosan coated monolith for nucleic acid capture in a thermoplastic microfluidic chip.

Biomicrofluidics 8(4) , 044109, (2014)

A technique for microfluidic, pH modulated DNA capture and purification using chitosan functionalized glycidyl methacrylate monoliths is presented. Highly porous polymer monoliths are formed and subse...

Expansion of CTCs from early stage lung cancer patients using a microfluidic co-culture model.

Oncotarget 5(23) , 12383-97, (2015)

The potential utility of circulating tumor cells (CTCs) to guide clinical care in oncology patients has gained momentum with emerging micro- and nanotechnologies. Establishing the role of CTCs in tumo...

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