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(R)-(+)- 8-羟基-DPAT氢溴酸盐

(R)-(+)- 8-羟基-DPAT氢溴酸盐名称

[ CAS 号 ]:
78095-19-9

[ 中文名 ]:
(R)-(+)-8-羟基-DPAT氢溴酸盐(8-羟基 DPAT)

[ 英文名 ]:
R(+)-8-Hydroxy DPAT HBr

[英文别名 ]:

C16H25NO.HBr

(R)-(+)- 8-羟基-DPAT氢溴酸盐物理化学性质

[ 分子式 ]:
C₁₆H₂₆BrNO

[ 分子量 ]:
328.28800

[ 精确质量 ]:
327.12000

[ PSA ]:
23.47000

[ LogP ]:
4.32960

[ 储存条件 ]:
2-8°C，密封，干燥

(R)-(+)- 8-羟基-DPAT氢溴酸盐MSDS

详细MSDS(安全技术说明书)

(R)-(+)- 8-羟基-DPAT氢溴酸盐安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 风险声明 (欧洲) ]:
36/37/38

[ 安全声明 (欧洲) ]:
22-26-36

[ 危险品运输编码 ]:
NONH for all modes of transport

(R)-(+)- 8-羟基-DPAT氢溴酸盐文献

Heregulin-HER3-HER2 signaling promotes matrix metalloproteinase-dependent blood-brain-barrier transendothelial migration of human breast cancer cell lines.

Oncotarget 6(6) , 3932-46, (2015)

HER2-positive breast tumors are associated with a high risk of brain relapse. HER3 is thought to be an indispensible signaling substrate for HER2 (encoded by ERBB2) and is induced in breast cancer-bra...

Serotonin 5-HT1A receptor in infancy-onset aggression: comparison with genetically defined aggression in adult rats.

Behav. Brain Res. 243 , 97-101, (2013)

Antisocial aggressive behavior in adolescents represents growing clinical and social problem. Previously the implication of 5-HT1A receptor in the regulation of fear-induced aggression was shown. Here...

Unilateral lesion of the nigrostriatal pathway decreases the response of GABA interneurons in the dorsal raphe nucleus to 5-HT(1A) receptor stimulation in the rat.

Neurochem. Int. 61(8) , 1344-56, (2012)

This study examined the firing rate and pattern of electrophysiologically and chemically identified GABA interneurons in the dorsal raphe nucleus (DRN), and role of 5-HT(1A) receptor agonist 8-OH-DPAT...

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