β-环糊精
β-环糊精用途
β-环糊精名称
[ CAS 号 ]:
7585-39-9
[ 中文名 ]:
β-环糊精
[ 英文名 ]:
β-cyclodextrin
[中文别名 ]:
[英文别名 ]:
- FEMA 4028
- cycloheptaamylose
- EINECS 231-493-2
- Cycloglucans
- betadex
- CARAWAY
- Cycloheptaglucosan
- Cvclodextrin
- beta-Cyclodextrin hydrate
- Klep
β-环糊精生物活性
[ 描述 ]:
[ 相关类别 ]:
[体外研究]
[参考文献]
[相关活性小分子]
β-环糊精物理化学性质
[ 密度 ]:
1.6±0.1 g/cm3
[ 沸点 ]:
1541.2±60.0 °C at 760 mmHg
[ 熔点 ]:
>260ºC (dec.)(lit.)
[ 分子式 ]:
C42H70O35
[ 分子量 ]:
1134.984
[ 闪点 ]:
885.9±32.9 °C
[ 精确质量 ]:
1134.369751
[ PSA ]:
554.05000
[ LogP ]:
-6.57
[ 外观性状 ]:
白色粉末
[ 蒸汽压 ]:
0.0±0.6 mmHg at 25°C
[ 折射率 ]:
1.591
[ 储存条件 ]:
+15C to +30C
[ 水溶解性 ]:
1 M NaOH: 50 mg/mL
β-环糊精MSDS
β-环糊精毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- GU2293000
- CHEMICAL NAME :
- beta-Cyclodextrin
- CAS REGISTRY NUMBER :
- 7585-39-9
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 12
- MOLECULAR FORMULA :
- C42-H70-O35
- MOLECULAR WEIGHT :
- 1135.12
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 18800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 26,287,1983
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 356 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 48THAM "Proceedings of the International Symposium on Cyclodextrins, 1st, 1981," Szejtli, J., ed., Hingham, MA, Kluwer Academic Pub., 1982 Volume(issue)/page/year: 1,109,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3700 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 26,287,1983
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1008 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AJPAA4 American Journal of Pathology. (Lippincott/Harper, Journal Fulfillment Dept., 2350 Virginia Ave., Hagerstown, MD 21740) V.1- 1925- Volume(issue)/page/year: 83,367,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >12500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PSSCBG Pesticide Science. (Blackwell Scientific Pub. Ltd., POB 88, Oxford, UK) V.1- 1970- Volume(issue)/page/year: 11,134,1980
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 330 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 48THAM "Proceedings of the International Symposium on Cyclodextrins, 1st, 1981," Szejtli, J., ed., Hingham, MA, Kluwer Academic Pub., 1982 Volume(issue)/page/year: 1,109,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 412 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 48THAM "Proceedings of the International Symposium on Cyclodextrins, 1st, 1981," Szejtli, J., ed., Hingham, MA, Kluwer Academic Pub., 1982 Volume(issue)/page/year: 1,109,1982 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 634 gm/kg/52W-C
- TOXIC EFFECTS :
- Liver - hepatitis (hepatocellular necrosis), zonal Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)
- REFERENCE :
- FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 33,367,1995 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 350 gm/kg
- SEX/DURATION :
- multigeneration
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - other effects Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)
- REFERENCE :
- REPTED Reproductive Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1987- Volume(issue)/page/year: 9,389,1995 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X2627 No. of Facilities: 21 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 123 (estimated) No. of Female Employees: 123 (estimated)
β-环糊精安全信息
[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ 危害码 (欧洲) ]:
Xi
[ 风险声明 (欧洲) ]:
R36/37/38
[ 安全声明 (欧洲) ]:
S26-S36
[ 危险品运输编码 ]:
NONH for all modes of transport
[ WGK德国 ]:
2
[ RTECS号 ]:
GU2293000
[ 海关编码 ]:
3505100000
β-环糊精合成路线
β-环糊精上下游产品
β-环糊精上游产品
β-环糊精下游产品
β-环糊精制备
一般从柑橘皮、苹果皮、葡萄皮、蚕砂和甜菜渣等植物细胞中用酸解法、酶解法和离子交换法提取。
β-环糊精海关
[ 海关编码 ]: 3505100000
β-环糊精文献
Biochemistry 53(25) , 4081-3, (2014)
Aggregation of α-synuclein has been implicated in Parkinson's disease (PD). While many compounds are known to inhibit α-synuclein aggregation, dissolution of aggregates into their constituent monomers...
CDDP supramolecular micelles fabricated from adamantine terminated mPEG and β-cyclodextrin based seven-armed poly (L-glutamic acid)/CDDP complexes.Colloids Surf. B Biointerfaces 105 , 31-6, (2013)
This research is aimed to develop a nano-sized supramolecular micelle delivery system of cis-dichlorodiammine platinum (II) (CDDP) in order to achieve the passive tumor targeting. Firstly, star-shaped...
Characterization of the hydrochlorothiazide: β-cyclodextrin inclusion complex. Experimental and theoretical methods.J. Phys. Chem. B 117(1) , 206-17, (2013)
Hydrochlorothiazide (HCT) is one of the most commonly prescribed antihypertensive drugs. In an attempt to gain an insight into the physicochemical and molecular aspects controlling the complex archite...
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价格:
¥348.0/500g
¥118.0/100g
联系人:刘佳
产品详情:β-环糊精
公司名:上海源溪生物科技有限公司
区域:上海市浦东新区
价格:
¥需询单/1g
联系人:赖经理
产品详情:β-Cyclodextrin
公司名:上海创赛科技有限公司
区域:上海市嘉定区
价格:
¥63.0/5g
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联系人:夏言
产品详情:[Perfemiker]β-环糊精,98%生物技术级
公司名:上海阿拉丁生化科技股份有限公司
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联系人:阿拉丁李高志
产品详情:β-环糊精
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相关化合物
【β-环糊精】化源网提供β-环糊精CAS号7585-39-9,β-环糊精MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询β-环糊精上化源网,专业又轻松。>>电脑版:β-环糊精
标题:β-环糊精_MSDS_用途_密度_CAS号【7585-39-9】_化源网 地址:https://www.chemsrc.com/amp/cas/7585-39-9_762755.html